A Novel High-Resolution Method for the Respiration Rate and Breathing Waveforms Remote Monitoring
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A search for robust noninvasive methods permitting to discern the respiration subtle peculiarities in mammals is a topical issue. A novel approach called “sorption-enhanced infrared thermography” (SEIRT), helping to solve this problem, is described. Its benefits spring from the integration of the infrared thermography (IRT) and chemical physics (phase transition heat release/absorption) within a single method. The SEIRT opportunities were verified in the investigation of 42 humans, 49 rats and 4 minipigs whose breathing waveforms were revealed to the last detail. It is shown that the SEIRT-obtained breathing-conditioned temperature response may exceed 10 °C (!) even in small animals (rats) and that the SEIRT sensitivity is 4.5–250 times higher than that of the matched IRT-based techniques. The new method is validated by a comparison with that based on thorax breathing movement (TBM). It is shown that the SEIRT-determined breaths have a close correlation with those determined via TBM (r = + 1.000, p ≪ 0.05); this is also true for breathing intervals (r = + 0.9772, p ≪ 0.05). SEIRT opens up the way to a high-resolution noncontact quantitative evaluation of respiration rate and breathing waveforms in both humans and animals. It may become a cutting-edge technique in diagnostic medicine and biomedical research.
KeywordsInfrared thermography Adsorption/desorption heat Breathing sorption indicator Mammals Humans Animals
Breathing sorption indicator
Sorption-enhanced infrared thermography
Thorax breathing movement
This work was supported by the Russian Foundation for Basic Research (Grant No. 18-08-00956). The author thanks V.I. Baranov for his technical assistance in the experiments with laboratory rats, E.G. Vergunov for his help in the statistical analysis, and D.S. Sergeevichev for his help in organizing the minipigs investigation.
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