Skip to main content
Log in

Thermal actuation and confinement of water droplets on paper-based digital microfluidics devices

  • Research Paper
  • Published:
Microfluidics and Nanofluidics Aims and scope Submit manuscript

Abstract

In this paper, the thermocapillary actuation is implemented to manipulate and confine the fluid droplets in a paper-based digital microfluidics (PB-DMF) device. The main advantage of using the thermocapillary actuation over the traditional electrowetting-on-dielectric actuation in the DMF devices is its ability to work with lower operating DC voltages. The proposed device is fabricated by the low-cost screen printing method using very low-cost materials. In order to overcome the weak controllability of the device over the droplets, a new thermal confinement technique is proposed which simply embedded in the device electrode pattern. A new thermally actuated valve is also designed to work based on thermocapillary actuation for switching on or off the droplets. The fabricated DMF device and the thermal valve are both combined with a microfluidics paper-based analytical device to form a hybrid paper chip in which the droplets are driven by both channel-based and droplet-based devices. The device operation is tested by using a biochemical glucose colorimetric detection assay.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6
Fig. 7
Fig. 8
Fig. 9
Fig. 10
Fig. 11
Fig. 12
Fig. 13
Fig. 14
Fig. 15
Fig. 16
Fig. 17

Similar content being viewed by others

References

  • Abadian A, Jafarabadi-Ashtiani S (2014) Paper-based digital microfluidics. Microfluid Nanofluid 16:989–995

    Article  Google Scholar 

  • Abadian A, Manesh SS, Ashtiani SJ (2017) Hybrid paper-based microfluidics: combination of paper-based analytical device (µPAD) and digital microfluidics (DMF) on a single substrate. Microfluid Nanofluid 21:65

    Article  Google Scholar 

  • Ainla A, Hamedi MM, Güder F, Whitesides GM (2017) Electrical textile valves for paper microfluidics. Adv Mater 29:1702894. https://doi.org/10.1002/adma.201702894

    Article  Google Scholar 

  • Altundemir S, Uguz A, Ulgen K (2017) A review on wax printed microfluidic paper-based devices for international health. Biomicrofluidics 11:041501

    Article  Google Scholar 

  • Chen JZ, Troian SM, Darhuber AA, Wagner S (2005) Effect of contact angle hysteresis on thermocapillary droplet actuation. J Appl Phys 97:014906

    Article  Google Scholar 

  • Chen H, Cogswell J, Anagnostopoulos C, Faghri M (2012) A fluidic diode, valves, and a sequential-loading circuit fabricated on layered paper. Lab Chip 12:2909–2913

    Article  Google Scholar 

  • Choi K, Ng AH, Fobel R, Wheeler AR (2012) Digital microfluidics. Annu Rev Anal Chem 5:413–440

    Article  Google Scholar 

  • Darhuber AA, Valentino JP, Davis JM, Troian SM, Wagner S (2003a) Microfluidic actuation by modulation of surface stresses. Appl Phys Lett 82:657–659

    Article  Google Scholar 

  • Darhuber AA, Valentino JP, Troian SM, Wagner S (2003b) Thermocapillary actuation of droplets on chemically patterned surfaces by programmable microheater arrays. J Microelectromech Syst 12:873–879

    Article  Google Scholar 

  • Darhuber AA, Valentino JP, Troian SM (2010) Planar digital nanoliter dispensing system based on thermocapillary actuation. Lab Chip 10:1061–1071

    Article  Google Scholar 

  • Davanlou A, Kumar R (2015a) Counter-current motion of a droplet levitated on a liquid film undergoing Marangoni convection. Int J Heat Mass Transf 89:345–352

    Article  Google Scholar 

  • Davanlou A, Kumar R (2015b) Thermally induced collision of droplets in an immiscible outer fluid. Sci Rep 5:9531

    Article  Google Scholar 

  • de Oliveira RA, Camargo F, Pesquero NC, Faria RC (2017) A simple method to produce 2D and 3D microfluidic paper-based analytical devices for clinical analysis. Anal Chim Acta 957:40–46

    Article  Google Scholar 

  • Delaney JL, Hogan CF, Tian J, Shen W (2011) Electrogenerated chemiluminescence detection in paper-based microfluidic sensors. Anal Chem 83:1300–1306

    Article  Google Scholar 

  • Fobel R, Kirby AE, Ng AH, Farnood RR, Wheeler AR (2014) Paper microfluidics goes digital. Adv Mater 26:2838–2843

    Article  Google Scholar 

  • Jiao Z, Huang X, Nguyen N-T, Abgrall P (2008) Thermocapillary actuation of droplet in a planar microchannel. Microfluid Nanofluid 5:205–214

    Article  Google Scholar 

  • Ko H et al (2014) Active digital microfluidic paper chips with inkjet-printed patterned electrodes. Adv Mater 26:2335–2340

    Article  Google Scholar 

  • Koo CK, He F, Nugen SR (2013) An inkjet-printed electrowetting valve for paper-fluidic sensors. Analyst 138:4998–5004

    Article  Google Scholar 

  • Li X, Tian J, Nguyen T, Shen W (2008) Paper-based microfluidic devices by plasma treatment. Anal Chem 80:9131–9134

    Article  Google Scholar 

  • Li X, Zwanenburg P, Liu X (2013) Magnetic timing valves for fluid control in paper-based microfluidics. Lab Chip 13:2609–2614

    Article  Google Scholar 

  • López-Marzo AM, Merkoçi A (2016) Paper-based sensors and assays: a success of the engineering design and the convergence of knowledge areas. Lab Chip 16:3150–3176

    Article  Google Scholar 

  • Martinez AW, Phillips ST, Butte MJ, Whitesides GM (2007) Patterned paper as a platform for inexpensive, low-volume, portable bioassays. Angew Chem Int Ed 46:1318–1320

    Article  Google Scholar 

  • Selva B, Miralles V, Cantat I, Jullien M-C (2010) Thermocapillary actuation by optimized resistor pattern: bubbles and droplets displacing, switching and trapping. Lab Chip 10:1835–1840

    Article  Google Scholar 

  • Wang W, Jones T (2011) Microfluidic actuation of insulating liquid droplets in a parallel-plate device. In: Journal of Physics: Conference Series, vol 1. IOP Publishing, p 012057

  • Yafia M, Shukla S, Najjaran H (2015) Fabrication of digital microfluidic devices on flexible paper-based and rigid substrates via screen printing. J Micromech Microeng 25:057001

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Shahin Jafarabadi Ashtiani.

Electronic supplementary material

Below is the link to the electronic supplementary material.

Supplementary material 1 (MP4 34941 kb)

Supplementary material 2 (MP4 48052 kb)

Supplementary material 3 (MP4 10691 kb)

Supplementary material 4 (MP4 22622 kb)

Supplementary material 5 (MP4 13871 kb)

Supplementary material 6 (MP4 12934 kb)

Supplementary material 7 (MP4 30409 kb)

Supplementary material 8 (MP4 14197 kb)

Supplementary material 9 (MP4 13446 kb)

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Atabakhsh, S., Jafarabadi Ashtiani, S. Thermal actuation and confinement of water droplets on paper-based digital microfluidics devices. Microfluid Nanofluid 22, 43 (2018). https://doi.org/10.1007/s10404-018-2060-6

Download citation

  • Received:

  • Accepted:

  • Published:

  • DOI: https://doi.org/10.1007/s10404-018-2060-6

Keywords

Navigation