Endoscopic ultrasonography for the evaluation of pancreatic cystic neoplasms

Abstract

Endoscopic ultrasonography (EUS) is a modality with high spatial resolution that enables comprehensive observation of the entire pancreas and plays an important role in the diagnosis of pancreatic lesions. Recent advances in diagnostic imaging methods such as ultrasound, computed tomography, and magnetic resonance imaging have increased the incidental detection of pancreatic cystic lesions (PCLs). EUS has been recognized as an essential diagnostic method for the detection and evaluation of PCLs. EUS has two important roles: as a detailed (high-resolution) imaging diagnostic method and as an approach for collecting cyst fluid content by EUS-guided fine needle aspiration for pathological diagnosis or biomarker evaluation. Furthermore, in recent years, the usefulness of contrast-enhanced EUS for the differential diagnosis of PCLs or evaluation of grade of malignancy, and a novel imaging technique called needle-based confocal laser endomicroscopy to observe intraductal structures through a needle, has been reported. An understanding of the morphological characteristics of PCLs depicted by ultrasound imaging and of the benefits and limitations of EUS diagnosis in daily practice is needed.

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Correspondence to Eizaburo Ohno.

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Ohno, E., Hirooka, Y., Kawashima, H. et al. Endoscopic ultrasonography for the evaluation of pancreatic cystic neoplasms. J Med Ultrasonics 47, 401–411 (2020). https://doi.org/10.1007/s10396-019-00980-0

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Keywords

  • Endoscopic ultrasound
  • Pancreatic cystic neoplasms
  • Contrast-enhanced endoscopic ultrasound
  • Endoscopic ultrasound-fine needle aspiration
  • Intraductal papillary mucinous neoplasm