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Esophagus

, Volume 15, Issue 3, pp 180–189 | Cite as

Clinical characteristics and management of gastric tube cancer after esophagectomy

  • Yasuhiro Shirakawa
  • Kazuhiro Noma
  • Naoaki Maeda
  • Takayuki Ninomiya
  • Shunsuke Tanabe
  • Satoru Kikuchi
  • Shinji Kuroda
  • Masahiko Nishizaki
  • Shunsuke Kagawa
  • Yoshiro Kawahara
  • Hiroyuki Okada
  • Toshiyoshi Fujiwara
Original Article
  • 103 Downloads

Abstract

Background

Gastric cancer is the second most common malignancy, overlapping with thoracic esophageal cancer (TEC). Among them, metachronous gastric tube cancers after TEC surgery have been increasing. The aims of this study were to examine the clinicopathological factors and treatment outcomes of gastric tube cancer (GTC) after TEC surgery.

Methods

Thirty-three GTCs in 30 cases after TEC treated between 1997 and 2016 were investigated retrospectively.

Results

Most cases were males. The median interval from TEC surgery to GTC occurrence was 57 (6.5–107.5) months. Almost 2/3 lesions occurred in the lower third of the gastric tube (21/33); 29 lesions (in 26 cases) were superficial cancers, and 4 lesions were advanced cancers. Twenty-two lesions of superficial cancer were differentiated type, and the remaining seven lesions were undifferentiated type. Treatment for superficial cancer had previously been performed with partial gastric tube resection (10 lesions), and the number of cases undergoing endoscopic submucosal dissection (ESD) had increased recently (19 lesions). Most cases with superficial cancer survived without relapse. Four lesions of advanced cancer were found after a relatively long interval following TEC surgery. Most lesions of advanced cancer were scirrhous, undifferentiated type, and they died due to GTC.

Conclusion

GTCs may occur late in the postoperative course following TEC surgery. If they are discovered at an early stage, these lesions can be cured with ESD. Long-term periodic endoscopic examinations after TEC surgery are important.

Keywords

Gastric tube cancer Esophagectomy Endoscopic submucosal dissection 

Notes

Compliance with ethical standards

Ethical Statement

All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) and with the Helsinki Declaration of 1964 and later versions.

Conflict of interest

The authors declare that they have no conflict of interest.

Informed consent

Informed consent or substitute for it was obtained from all patients for being included in the study.

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Copyright information

© The Japan Esophageal Society and Springer Japan KK, part of Springer Nature 2018

Authors and Affiliations

  • Yasuhiro Shirakawa
    • 1
  • Kazuhiro Noma
    • 1
  • Naoaki Maeda
    • 1
  • Takayuki Ninomiya
    • 1
  • Shunsuke Tanabe
    • 1
  • Satoru Kikuchi
    • 1
  • Shinji Kuroda
    • 1
  • Masahiko Nishizaki
    • 1
  • Shunsuke Kagawa
    • 1
  • Yoshiro Kawahara
    • 2
  • Hiroyuki Okada
    • 2
  • Toshiyoshi Fujiwara
    • 1
  1. 1.Department of Gastroenterological Surgery, Graduate School of Medicine, Dentistry and Pharmaceutical SciencesOkayama UniversityOkayamaJapan
  2. 2.Department of Gastroenterology and Hepatology, Graduate School of Medicine, Dentistry and Pharmaceutical SciencesOkayama UniversityOkayamaJapan

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