Myopia progression over a 4-year period after laser-assisted refractive surgery in patients in their 20s and 30s

Abstract

Purpose

To investigate the increase in refractive error (RE) and axial length (AL) in myopia patients in their 20s and 30s after laser-assisted in situ keratomileusis (LASIK) or epipolis-LASIK (epi-LASIK).

Study design

Retrospective cohort study.

Methods

This retrospective study involved 280 eyes of 140 myopia patients who underwent LASIK or epi-LASIK at the Baptist Eye Institute, Kyoto, Japan and who were followed for more than 5 years postoperatively. The patients were divided into 2 groups according to age: group A (age range, 20–29 years) and group B (age range, 30–39 years). In all patients, the RE and AL were measured at 1, 2, 3, 4, and 5 years postoperatively, and the 2 groups were compared in terms of each surgical method.

Results

The patients’ mean age at surgery was 30.6 ± 4.9 years. No significant difference was found between the 2 groups in terms of the preoperative mean spherical equivalent (SE) or AL. In the LASIK group, the mean changes in SE during the 4 years of study in groups A and B were + 0.054 ± 0.256 D and + 0.052 ± 0.327 D, respectively (P = .93, NS), and the postoperative increases in AL were 0.059 ± 0.134 mm and 0.027 ± 0.133 mm, respectively (P = .08, NS). In the epi-LASIK group, the mean change in SE during the 4 years of study in groups A and B were  −0.438 ± 0.207 D and −0.259 ± 0.454 D, respectively (P = .41, NS), and the postoperative increases in AL were 0.124 ± 0.141 mm and 0.094 ± 0.166 mm, respectively (P = .46, NS).

Conclusion

Our findings showed no significant difference in myopia progression in patients in their 20s and 30s during a 4-year period after either LASIK or epi-LASIK.

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References

  1. 1.

    Sella S, Duvdevan-Strier N, Kaiserman I. Unilateral refractive surgery and myopia progression. J Pediatr Ophthalmol Strabismus. 2019;56:78–82.

    Article  Google Scholar 

  2. 2.

    Eye Disease Prevalence Research Group. The prevalence of refractive errors among adults in the United States, Western Europe, and Australia. Arch Ophthalmol. 2004;122:495–505.

    Article  Google Scholar 

  3. 3.

    Lam CS, Goldschmidt E, Edwards M. Prevalence of myopia in local and international schools in Hong Kong. Optom Vis Sci. 2004;81:317–22.

    Article  Google Scholar 

  4. 4.

    Gross DA, Winkler RL. Progression of myopia in youth: age of cessation. Am J Optom Physiol Opt. 1983;60:651–8.

    Article  Google Scholar 

  5. 5.

    Bullimore MA, Jones LA, Moeschberger ML, Zadnik K, Payor RE. A retrospective study of myopia progression in adult contact lens wearers. Invest Ophthalmol Vis Sci. 2002;43:2110–3.

    PubMed  Google Scholar 

  6. 6.

    Song YY, Wang H, Wang BS, Qi H, Rong ZX, Chen HZ. Atropine in ameliorating the progression of myopia in children with mild to moderate myopia: a meta-analysis of controlled clinical trials. J Ocular Pharmacol. 2011;27:361–8.

    CAS  Article  Google Scholar 

  7. 7.

    Li SM, Kang MT, Wu SS, Meng B, Sun YY, Wei SF, et al. Studies using concentric ring bifocal and peripheral add multifocal contact lenses to slow myopia progression in school-aged children: a meta-analysis. Ophthalmic Physiol Opt. 2017;37:51–9.

    Article  Google Scholar 

  8. 8.

    Hiraoka T, Kakita T, Okamoto F, Takahashi H, Oshika T. Long-term effect of overnight orthokeratology on axial length elongation in childhood myopia: a 5-year follow-up study. Invest Ophthalmol Vis Sci. 2012;53:3913–9.

    Article  Google Scholar 

  9. 9.

    Ma L, Atchison DA, Charman WN. Off-axis refraction and aberrations following conventional laser in situ keratomileusis. J Cataract Refract Surg. 2005;31:489–98.

    Article  Google Scholar 

  10. 10.

    Ellingsen KI, Nizam A, Ellingsen BA, Lynn MJ. Age-related refractive shifts in simple myopia. J Refract Surg. 1997;13:223–8.

    CAS  PubMed  Google Scholar 

  11. 11.

    Fan L, Xiong L, Zhang B, Wang Z. Longitudinal and regional non-uniform remodeling of corneal epithelium after topography-guided FS-LASIK. J Refract Surg. 2019;35:88–95.

    Article  Google Scholar 

  12. 12.

    Nakamura Y, Hieda O, Yamamura K, Wakimasu K, Yokota I, Kinoshita S. Comparative study of seven-year outcomes following laser in situ keratomileusis with those of trans-epithelial photorefractive keratectomy. Nippon Ganka Gakkai Zasshi. 2016;120:487–93 [in Japanese].

    PubMed  Google Scholar 

  13. 13.

    Huang J, Wen D, Wang Q, McAlinden C, Flitcroft I, Chen H, et al. Efficacy comparison of 16 interventions for myopia control in children: a network meta-analysis. Ophthalmology. 2016;123:697–708.

    Article  Google Scholar 

  14. 14.

    Gwiazda J, Thorn F, Bauer J, Held R. Myopic children show insufficient accommodative response to blur. Invest Ophthalmol Vis Sci. 1993;34:690–4.

    CAS  PubMed  Google Scholar 

  15. 15.

    Smith EL 3rd, Kee CS, Ramamirtham R, Qiao-Grider Y, Hung LF. Peripheral vision can influence eye growth and refractive development in infant monkeys. Invest Ophthalmol Vis Sci. 2005;46:3965–72.

    Article  Google Scholar 

  16. 16.

    Benavente-Perez A, Nour A, Troilo D. Axial eye growth and refractive error development can be modified by exposing the peripheral retina to relative myopic or hyperopic defocus. Invest Ophthalmol Vis Sci. 2014;10:6765–73.

    Article  Google Scholar 

  17. 17.

    McBrien NA, Adams DW. A longitudinal investigation of adult-onset and adult-progression of myopia in an occupational group. Invest Ophthalmol Vis Sci. 1997;38:321–33.

    CAS  PubMed  Google Scholar 

  18. 18.

    Grosvenor T, Scott R. Three-year changes in refraction and its components in youth-onset and early adult-onset myopia. Optom Vis Sci. 1993;70:677–83.

    CAS  Article  Google Scholar 

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Acknowledgements

The authors wish to thank John Bush for reviewing the manuscript.

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Correspondence to Miho Sasaki.

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M. Sasaki, None; O. Hieda, None; K. Wakimasu, None; K. Yamamura, None; S. Kinoshita, None; C. Sotozono, None.

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Corresponding Author: Miho Sasaki

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Sasaki, M., Hieda, O., Wakimasu, K. et al. Myopia progression over a 4-year period after laser-assisted refractive surgery in patients in their 20s and 30s. Jpn J Ophthalmol 64, 450–454 (2020). https://doi.org/10.1007/s10384-020-00751-2

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Keywords

  • Age
  • Disease progression
  • Epi-LASIK
  • LASIK
  • Myopia