Effects of cataract surgery on symptoms and findings of dry eye in subjects with and without preexisting dry eye

Abstract

Purpose

To compare dry eye symptoms and findings in post cataract surgery eyes’ with and without preexisting dry eye.

Study design

Prospective, observational case–control study.

Methods

Sixty-seven eyes that had undergone cataract surgery were included; 48 were classified into group D (preexisting dry eye) and 19 into group N (no preexisting dry eye). No subjects received perioperative treatment for dry eye. We evaluated between-group differences in symptom scores, corrected distance visual acuity (CDVA), tear film breakup time (BUT), tear film breakup pattern (BUP), and ocular surface fluorescein staining scores, at 1 week, 1 month, and 3 months postoperatively.

Results

Symptoms were unchanged in group N, but improved in group D (P < .001) postoperatively. CDVA was improved after surgery in both groups (P < .001). BUT was shorter preoperatively in group D than in group N although this difference was absent 1 month postoperatively. Fluorescein staining scores significantly increased at 1 month postoperatively in group N (P = .01), but did not change in group D. During the perioperative period, the predominant BUP was the random break pattern in both groups (≥ 85%). From 1 week to 3 months, dimple break patterns decreased in group D (P = .007), whereas spot break patterns increased (P = .01).

Conclusions

Cataract surgery has an influence on tear film stability and the ocular surface. There was either a transient improvement or worsening of ocular surface wettability in some patients without preexisting dry eye.

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Acknowledgements

N. Maeda, Grant (Japanese Ministry of the Education, Culture, Sports, Science and Technology and Japanese Ministry of Health, Labor and Welfare)

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Affiliations

Authors

Contributions

Study concept and design (MS, NM, SK, KA, RK, KN); data collection (MK, KA, RK); analysis and interpretation of data (MS, NM, SK, KA, RK, KN); writing the manuscript (MS, NM, SK); critical revision of the manuscript (MS, NM, SK, KA, RK, KN). All authors read and approved the final manuscript.

Corresponding author

Correspondence to Naoyuki Maeda.

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Conflicts of interest

M. Shimabukuro, None; N. Maeda, Lecture fee (AMO, Alcon, Bausch + Lomb, HOYA, Oculus, Santen, Senjyu, Tomey, Menicon, Pfizer); S. Koh, Grant (Seed); K. Abe, None; R. Kobayashi, None; K. Nishida, Grant and Lecture fee (Senjyu, Otsuka, Santen), Grant, Lecture fee and Consultant fee (Novartis).

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Corresponding Author: Naoyuki Maeda

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Shimabukuro, M., Maeda, N., Koh, S. et al. Effects of cataract surgery on symptoms and findings of dry eye in subjects with and without preexisting dry eye. Jpn J Ophthalmol 64, 429–436 (2020). https://doi.org/10.1007/s10384-020-00744-1

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Keywords

  • Cataract surgery
  • Dry eye
  • Tear film breakup pattern
  • Tear film breakup time