Skip to main content
SpringerLink
Log in

Torquated large ovarian lymphoma as a cause of acute abdomen: a case report of diffuse large B-cell ovarian lymphoma with a germinal center B-cell-like phenotype

  • case report
  • Published:
Wiener Medizinische Wochenschrift Aims and scope Submit manuscript

Summary

Background

Ovarian lymphoma is a rare neoplasm and most commonly represents secondary ovarian involvement in overt systemic disease, usually of the non-Hodgkin’s type.

Aim

To report a case of acute abdomen caused by torquated large ovarian lymphoma.

Case report

We report the case of 65-year-old patient admitted to our hospital with signs and symptoms of acute abdomen. Findings were suggestive of left ovary torsion due to the neoplasm. After detorsion, mobilization, and adhesiolysis, a bilateral adnexectomy was performed. Histopathological and immunohistochemical analysis of the left ovarian tumor was performed and diagnosis of diffuse large B‑cell lymphoma (DLBCL) with a GCB (germinal center B‑cell-like) phenotype was made. Additional bone marrow biopsy and imaging techniques excluded other sites of involvement, confirming diagnosis of primary ovarian DLBCL.

Conclusion

The prognosis of ovarian lymphomas may be poorer than for other lymphomas because of late diagnosis. The best treatment option appears to be systemic chemotherapy.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Chorlton I, Norris HJ, King FM. Malignant reticuloendothelial disease involving the ovary as a primary manifestation: a series of 19 lymphomas and 1 granulocytic sarcoma. Cancer. 1974;34:397–407.

    Article  CAS  Google Scholar 

  2. Senol T, Doger E, Kahramanoglu I, Geduk A, Kole E, Yucesoy I, et al. Five cases of non-Hodgkin B‑cell lymphoma of the ovary. Case Rep Obstet Gynecol. 2014. https://doi.org/10.1155/2014/392758.

    Article  PubMed  PubMed Central  Google Scholar 

  3. Dimopoulos MA, Daliani D, Pugh W, Gershenson D, Cabanillas F, Sarris AH. Primary ovarian non-Hodgkin’s lymphoma: Outcome after treatment with combination chemotherapy. Gynecol Oncol. 1997;64:446–50.

    Article  CAS  Google Scholar 

  4. Monterroso V, Jaffe ES, Merino MJ, Medeiros LJ. Malignant lymphomas involving the ovary: a clinicopathologic analysis of 39 cases. Am J Surg Path. 1993;17:154–70.

    Article  CAS  Google Scholar 

  5. Weingertner AS, Hamid D, Roedlich MN, Baldauf JJ. Non-Hodgkin malignant lymphoma revealed by an ovarian tumor case report and review of the literature. Gynecol Oncol. 2004;95:750–4.

    Article  CAS  Google Scholar 

  6. Vang R, Medeiros LJ, Fuller GN, Sarris AH, Deavers M. Non-Hodgkin’s lymphoma involving the gynecologic tract. A review of 88 cases. Adv Anat Pathol. 2001;8:200–17.

    Article  CAS  Google Scholar 

  7. Elharroudi T, Ismaili N, Errihani H, Jalil A. Primary lymphoma of the ovary. J Cancer Res Ther. 2008;4:195–6.

    Article  Google Scholar 

  8. Crasta JA, Vallikad E. Ovarian lymphoma. Indian J Med Paediatr Oncol. 2009;30:28–30.

    PubMed  PubMed Central  Google Scholar 

  9. Komoto D, Nishiyama Y, Yamamoto Y, Monden T, Sasakawa Y, Toyama Y, et al. A case of non-Hodgkin’s lymphoma of the ovary: Usefulness of 18F-FDG PET for staging and assessment of the therapeutic response. Ann Nucl Med. 2006;20:157–60.

    Article  Google Scholar 

  10. Sakurai N, Tateoka K, Taguchi J, Terada T. Primary precursor B‑cell lymphoblastic lymphoma of the ovary: Case report and review of the literature. Int J Gynecol Pathol. 2008;27:412–7.

    Article  Google Scholar 

  11. Feugier P, Van Hoof A, Sebban C, Solal-Celigny P, Bouabdallah R, Fermé C, et al. Long-term results of the R‑CHOP study in the treatment of elderly patients with diffuse large B‑cell lymphoma: a study by the Groupe d’Etude des Lymphomes de l’Adulte. J Clin Oncol. 2005;23:4117–26.

    Article  CAS  Google Scholar 

Download references

Acknowledgements

We would like to thank the operating room staff and nurses for their generous assistance. We would also like to thank the patient.

Author information

Authors and Affiliations

  1. “Sveti Duh” University Hospital, Department of Obstetrics and Gynecology, University of Zagreb, School of Medicine, Zagreb, Croatia

    Krešimir Živković MD, MSc, PhD,  Ingrid Marton MD, MSc, PhD,  Ana Tikvica Luetić MD, MSc, PhD &  Dubravko Habek MD, MSc, PhD

  2. “Sveti Duh” University Hospital, Department of Obstetrics and Gynecology, Catholic University of Croatia, Zagreb, Croatia

    Ingrid Marton MD, MSc, PhD,  Ana Tikvica Luetić MD, MSc, PhD &  Dubravko Habek MD, MSc, PhD

  3. Merkur University Hospital, Department of Pathology and Cytology, University of Zagreb, School of Medicine, Zagreb, Croatia

    Slavko Gašparov MD, MSc, PhD & Katarina Horvat Pavlov MD

  4. Department of Pediatric Surgery, Children’s Hospital Zagreb, Zagreb, Croatia

    Ljudevit Sović MD

  5. Department of Gynecology and Obstetrics, General Hospital Tešanj, Braće Pobrić 17, 74260, Tešanj, Bosnia and Herzegovina

    Anis Cerovac MD, PhD Student

  6. Department of Anatomy, University of Tuzla, School of Medicine, Tuzla, Bosnia and Herzegovina

    Anis Cerovac MD, PhD Student

Authors
  1. Krešimir Živković MD, MSc, PhD
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Ingrid Marton MD, MSc, PhD
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Ana Tikvica Luetić MD, MSc, PhD
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Slavko Gašparov MD, MSc, PhD
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Katarina Horvat Pavlov MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Ljudevit Sović MD
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Anis Cerovac MD, PhD Student
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Dubravko Habek MD, MSc, PhD
    View author publications

    You can also search for this author in PubMed Google Scholar

Contributions

K. Živković and I. Marton wrote the manuscript. All other authors critically reviewed the manuscript, gave suggestions for improvements, and wrote some additions. K. Živković and D. Habek operated this patient in the emergency gynecological unit. S. Gašparov and K. Horvat Pavlov made the pathohistological diagnosis. All authors meet the criteria of authorship and have rights to intellectual content.

Corresponding author

Correspondence to Anis Cerovac MD, PhD Student.

Ethics declarations

Conflict of interest

K. Živković, I. Marton, A. Tikvica Luetić, S. Gašparov, K. Horvat Pavlov, L. Sović, A. Cerovac, and D. Habek declare that they have no competing interests.

Ethical standards

For this article no studies with human participants or animals were performed by any of the authors. All studies mentioned were in accordance with the ethical standards indicated in each case. For images or other information within the manuscript which identify patients, consent was obtained from them and/or their legal guardians.

Additional information

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Živković, K., Marton, I., Tikvica Luetić, A. et al. Torquated large ovarian lymphoma as a cause of acute abdomen: a case report of diffuse large B-cell ovarian lymphoma with a germinal center B-cell-like phenotype. Wien Med Wochenschr 172, 181–183 (2022). https://doi.org/10.1007/s10354-021-00823-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10354-021-00823-z

Keywords

Search

Navigation