Radiofrequency ablation of thyroid nodules: “Good Clinical Practice Recommendations” for Austria

An interdisciplinary statement from the following professional associations: Austrian Thyroid Association (ÖSDG), Austrian Society for Nuclear Medicine and Molecular Imaging (OGNMB), Austrian Society for Endocrinology and Metabolism (ÖGES), Surgical Endocrinology Working Group (ACE) of the Austrian Surgical Society (OEGCH)

Summary

The present “Good Clinical Practice Recommendations” relate to radiofrequency ablation (RFA) training, execution, and quality control, as well as to pre- and postinterventional standards of care. They are aimed at all physicians who intend to learn to perform, or who are already conducting RFA interventions as well as at thyroid specialists providing pre- and postoperative care to RFA patients in Austria. Adoption of these recommendations is strongly encouraged by the afore-listed professional associations.

All RFA interventionists who adhere to these standards shall be listed on a homepage linked to these professional associations entitled “RFA centers in compliance with the GCP recommendations of the ÖSDG/OGNMB/ÖGES/OEGCH-ACE.” This will ensure harmonization of RFA training and quality control in the performance of the treatment in Austria.

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References

  1. 1.

    Kim YS, Rhim H, Tae K, et al. Radiofrequency ablation of benign cold thyroid nodules: initial clinical experience. Thyroid. 2006;16:361–7.

    Article  Google Scholar 

  2. 2.

    Jeong WK, Baek JH, Rhim H, et al. Radiofrequency ablation of benign thyroid nodules: safety and imaging follow-up in 236 patients. Eur Radiol. 2008;18:1244–50.

    Article  Google Scholar 

  3. 3.

    Baek JH, Kim YS, Lee D, et al. Benign predominantly solid thyroid nodules: prospective study of efficacy of sonographically guided radiofrequency ablation versus control condition. AJR Am J Roentgenol. 2010;194:1137–42.

    Article  Google Scholar 

  4. 4.

    Sung JY, Baek JH, Kim KS, et al. Single-session treatment of benign cystic thyroid nodules with ethanol versus radiofrequency ablation: a prospective randomized study. Radiology. 2013;269:293–300.

    Article  Google Scholar 

  5. 5.

    Dobrinja C, Bernardi S, Fabris B, et al. Surgical and pathological changes after radiofrequency ablation of thyroid nodules. Int J Endocrinol. 2015; https://doi.org/10.1155/2015/576576.

    Article  PubMed  PubMed Central  Google Scholar 

  6. 6.

    Che Y, Jin S, Shi C, et al. Treatment of benign thyroid nodules: comparison of surgery with radiofrequency ablation. AJNR Am J Neuroradiol. 2015;36:1321–5.

    CAS  Article  Google Scholar 

  7. 7.

    Deandrea M, Sung JY, Limone P, et al. Efficacy and safety of radiofrequency ablation versus observation for nonfunctioning benign thyroid nodules: a randomized controlled international collaborative trial. Thyroid. 2015;25:890–6.

    Article  Google Scholar 

  8. 8.

    Valcavi R, Tsamatropoulos P. Health-related quality of life after percutaneous radiofrequency ablation of cold, solid, benign thyroid nodules: a 2-year follow-up study in 40 patients. Endocr Pract. 2015;21:887–96.

    Article  Google Scholar 

  9. 9.

    Cesareo R, Pasqualini V, Simeoni C, et al. Prospective study of effectiveness of ultrasound-guided radiofrequency ablation versus control group in patients affected by benign thyroid nodules. J Clin Endocrinol Metab. 2015;100:460–6.

    CAS  Article  Google Scholar 

  10. 10.

    Dobnig H, Amrein K. Monopolar radiofrequency ablation of thyroid nodules: a prospective Austrian single-center study. Thyroid. 2018;28:472–80.

    CAS  Article  Google Scholar 

  11. 11.

    Chen F, Tian G, Kong D, et al. Radiofrequency ablation for treatment of benign thyroid nodules: a PRISMA-compliant systematic review and meta-analysis of outcomes. Medicine. 2016; https://doi.org/10.1097/MD.0000000000004659.

    Article  PubMed  PubMed Central  Google Scholar 

  12. 12.

    Jung SL, Baek JH, Lee JH, et al. Efficacy and safety of radiofrequency ablation for benign thyroid nodules: a prospective multicenter study. Korean J Radiol. 2018;19:167–74.

    Article  Google Scholar 

  13. 13.

    Ha EJ, Baek JH, Kim KW, et al. Comparative efficacy of radiofrequency and laser ablation for the treatment of benign thyroid nodules: systematic review including traditional pooling and bayesian network meta-analysis. J Clin Endocrinol Metab. 2015;100:1903–11.

    CAS  Article  Google Scholar 

  14. 14.

    Li XL, Xu HX, Lu F, et al. Treatment efficacy and safety of ultrasound-guided percutaneous bipolar radiofrequency ablation for benign thyroid nodules. Br J Radiol. 2016; https://doi.org/10.1259/bjr.20150858.

    Article  PubMed  PubMed Central  Google Scholar 

  15. 15.

    Kohlhase KD, Korkusuz Y, Groner D, et al. Bipolar radiofrequency ablation of benign thyroid nodules using a multiple overlapping shot technique in a 3-month follow-up. Int J Hyperthermia. 2016;32:511–6.

    Article  Google Scholar 

  16. 16.

    Korkusuz Y, Mader A, Groner D, et al. Comparison of mono- and bipolar radiofrequency ablation in benign thyroid disease. World J Surg. 2017;41:2530–7.

    Article  Google Scholar 

  17. 17.

    Barile A, Quarchioni S, Bruno F, et al. Interventional radiology of the thyroid gland: critical review and state of the art. Gland Surg. 2018;7:132–46.

    Article  Google Scholar 

  18. 18.

    Gharib H, Hegedus L, Pacella CM, et al. Clinical review: nonsurgical, image-guided, minimally invasive therapy for thyroid nodules. J Clin Endocrinol Metab. 2013;98:3949–57.

    CAS  Article  Google Scholar 

  19. 19.

    Na DG, Lee JH, Jung SL, et al. Radiofrequency ablation of benign thyroid nodules and recurrent thyroid cancers: consensus statement and recommendations. Korean J Radiol. 2012;13:117–25.

    Article  Google Scholar 

  20. 20.

    Kim JH, Baek JH, Lim HK, et al. 2017 thyroid radiofrequency ablation guideline: Korean society of thyroid radiology. Korean J Radiol. 2018;19:632–55.

    Article  Google Scholar 

  21. 21.

    Garberoglio R, Aliberti C, Appetecchia M, et al. Radiofrequency ablation for thyroid nodules: which indications? The first Italian opinion statement. J Ultrasound. 2015;18:423–30.

    Article  Google Scholar 

  22. 22.

    Gharib H, Papini E, Garber JR, et al. American Association of Clinical Endocrinologists, American College of Endocrinology, and Associazione Medici Endocrinologi Medical guidelines for clinical practice for the diagnosis and management of thyroid nodules—2016 update. Endocr Pract. 2016;22:622–39.

    Article  Google Scholar 

  23. 23.

    Zhang M, Luo Y, Zhang Y, et al. Efficacy and safety of ultrasound-guided radiofrequency ablation for treating low-risk papillary thyroid microcarcinoma: a prospective study. Thyroid. 2016;26:1581–7.

    Article  Google Scholar 

  24. 24.

    P. Mikosch, H. J. Gallowitsch, E. Kresnik, J. Jester, F.G. Würtz, K. Kerschbaumer, O. Unterweger, H.P. Dinges, P. Lind, (2000) Value of ultrasound-guided fine-needle aspiration biopsy of thyroid nodules in an endemic goitre area. European Journal of Nuclear Medicine 27 (1):62-69

    CAS  Article  Google Scholar 

  25. 25.

    Wang JF, Wu T, Hu KP, et al. Complications following radiofrequency ablation of benign thyroid nodules: A systematic review. Chin Med J 2017;130:1361-70.

    Article  Google Scholar 

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Correspondence to Harald Dobnig M.D..

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H. Dobnig, W. Zechmann, M. Hermann, M. Lehner, D. Heute, S. Mirzaei, A. Gessl, V. Stepan, G. Höfle, P. Riss, and A. Simon declare that they have no competing interests.

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Dobnig, H., Zechmann, W., Hermann, M. et al. Radiofrequency ablation of thyroid nodules: “Good Clinical Practice Recommendations” for Austria. Wien Med Wochenschr 170, 6–14 (2020). https://doi.org/10.1007/s10354-019-0682-2

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Keywords

  • Thermoablation
  • RFA
  • Statement
  • GCP
  • Monopolar
  • Bipolar