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Research of cervical cytology screening in diagnosis of 370,000 cases with cervical lesion in Guangdong

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The Chinese-German Journal of Clinical Oncology

Abstract

Objective

Analysis of the results of 37 million cases by using cervical liquid-based cytology screening, discussion the situation of cervical cancer and precancerous lesions in Guangdong province.

Methods

From 2002 to 2006, using liquid-based thin-layer cytology (TCT) method screening cervical lesions within 371,929 women in Guangdong. Cytological diagnosis adopt TBS (the Bethesda system) Standard (TBS improved 2001 version of the diagnostic criteria), statistic positive rate by age and region respectively.

Results

371,929 cases of gynecology cervical samples in Guangdong, 331,251 cases were negative, accounted for 91.23%; cytology positive cases: 32,548 cases were squamous intraepithelial lesions (8.96%), 486 cases were glandular epithelial lesions (0.13%); grouped according to age: 30 to 40-year-old positive rate was 9.13%, 40 to 50-year-old positive rate was 9.60%, the latter had higher cytology positive rate; grouped according to region: the total samples in PRD areas were 304.951 cases, accounted for 81.99%, in which 24301 cases were positive (8.14%), in 66978 cases (18.01%) of NON-PRD regions, 7645 cases were positive (11.87%), there were 1858 cases had biopsy/follow-up results from 2004 to 2005, and the rate was 2.88%.

Conclusion

The cytological positive rate of cervical cancer and its precancerous lesions was 9.09% in Guangdong (of which the rate of cytological diagnosis as precancerous lesions was 3.40%), 30 to 50 age group had the high incidence of cervical cancer and its precursor lesions, and also the main stage of prevention for cervical cancer. Cytology positive rate was 11.87% in economic underdevelopment Non-Pearl River Delta regions, much higher than the Pearl River Delta region.

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Correspondence to Baowen Zheng.

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Zheng, B., Chen, C., Wei, A. et al. Research of cervical cytology screening in diagnosis of 370,000 cases with cervical lesion in Guangdong. Chin. -Ger. J. Clin. Oncol. 8, 90–94 (2009). https://doi.org/10.1007/s10330-008-0126-8

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  • DOI: https://doi.org/10.1007/s10330-008-0126-8

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