A 20-year evolution of cardiac performance in microgravity in a male astronaut

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Data availability

The datasets generated during and analyzed during the current study are not publicly available due to protect the medical data of the participant but are available from the corresponding author on reasonable request.

Change history

  • 28 November 2020

    Unfortunately, the first name of 8th author was incorrectly published in the original publication.

References

  1. 1.

    Almeida-Santos MA, Barreto-Filho JA, Oliveira JL, Reis FP, da Cunha Oliveira CC, Sousa AC (2016) Aging, heart rate variability and patterns of autonomic regulation of the heart. Arch Gerontol Geriatr 63:1–8

    Article  Google Scholar 

  2. 2.

    Brandfonbrener M, Landowne M, Shock NW (1955) Changes in cardiac output with age. Circulation 12:557–566

    CAS  Article  Google Scholar 

  3. 3.

    Eckberg DL, Diedrich A, Cooke WH, et al (2016) Respiratory modulation of human autonomic function: long-term neuroplasticity in space. J Physiol 594:5629–5646

    CAS  Article  Google Scholar 

  4. 4.

    Jones PP, Shapiro LF, Keisling GA, et al (2001) Altered autonomic support of arterial blood pressure with age in healthy men. Circulation 104:2424–2429

    CAS  Article  Google Scholar 

  5. 5.

    Kovacs GTA, Shadden M (2017) Analysis of age as a factor in NASA astronaut selection and career landmarks. PLoS ONE 12:e0181381

    Article  Google Scholar 

  6. 6.

    Limper U, Gauger P, Beck P, Krainski F, May F, Beck LE (2014) Interactions of the human cardiopulmonary, hormonal and body fluid systems in parabolic flight. Eur J Appl Physiol 114:1281–1295

    CAS  Article  Google Scholar 

  7. 7.

    Perhonen MA, Franco F, Lane LD, et al (2001) Cardiac atrophy after bed rest and spaceflight. J Appl Physiol 91:645–653

    CAS  Article  Google Scholar 

  8. 8.

    Prisk GK, Verhaeghe S, Padeken D, Hamacher H, Paiva M (2001) Three-dimensional ballistocardiography and respiratory motion in sustained microgravity. Aviat Space Environ Med 72:1067–1074

    CAS  PubMed  Google Scholar 

  9. 9.

    Rossum AC, Ziegler MG, Meck JV (2001) Effect of spaceflight on cardiovascular responses to upright posture in a 77-year-old astronaut. Am J Cardiol 88:1335–1337

    CAS  Article  Google Scholar 

  10. 10.

    Shibao C, Grijalva CG, Raj SR, Biaggioni I, Griffin MR (2007) Orthostatic hypotension-related hospitalizations in the United States. Am J Med 120:975–980

    Article  Google Scholar 

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Acknowledgements

This work was supported by the Grants 50WB1255 and 50WB1517 of the German Federal Ministry for Economic Affairs and Energy. We are grateful to the German Aerospace Center for providing the flight opportunity during the 22nd DLR Parabolic Flight Campaign. We are also thankful to Wolfram Sies for his technical support and to the appointees of NOVESPACE for all their skillful help.

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Contributions

UL, SM, GKP, AG, PFM, PG, LEJB, HWS contributed substantially to conception and design of the study. UL, SM, GKP, AG, PFM, PG, HWS performed data acquisition. UL, SM, JT, KH, FH, AG performed statistical data analysis. UL, SM, JT, GKP, KH, FH, AG, PFM, PG, LEJB, HWS, BDL, JJ contributed to interpretation of the data of the work. UL and JJ wrote the first draft of the manuscript. All authors contributed to manuscript revision, read and approved the submitted version.

Corresponding author

Correspondence to Ulrich Limper.

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Limper, U., Moestl, S., Tank, J. et al. A 20-year evolution of cardiac performance in microgravity in a male astronaut. Clin Auton Res (2020). https://doi.org/10.1007/s10286-019-00657-1

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