Résumé
Cette mise au point des connaissances actuelles permet d’individualiser certaines tumeurs malignes rares de l’ovaire (TMRO) et de préciser les indications de consultation d’oncogénétique pour les cliniciens. Contrairement aux cancers de l’ovaire classiques survenant à un âge jeune évoquant une mutation des gènes BRCA ou un syndrome de Lynch, la découverte d’une tumeur rare de l’ovaire même à un âge jeune n’évoque pas forcément une origine génétique et est le plus souvent sans rapport avec ces maladies génétiques.
Abstract
This development of the current knowledge allows individualizing some rare malignant ovarian tumors and specifying the indications of oncogenetics consultation for the clinicians. Contrary to the classic ovarian cancers arising at a young age evoking a BRCA mutation, the discovery of a rare ovarian tumor at a young age does not evoke necessarily a genetic origin and mostly without relationship with the BRCA genes.
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Lortholary, A., Yvard, A., Dugast, C. et al. Oncogénétique et tumeurs malignes rares de l’ovaire (TMRO). Oncologie 16, 330–334 (2014). https://doi.org/10.1007/s10269-014-2406-y
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DOI: https://doi.org/10.1007/s10269-014-2406-y