Skip to main content
Log in

Some challenges for statistics

  • Original Article
  • Published:
Statistical Methods and Applications Aims and scope Submit manuscript

Abstract

The paper gives a highly personal sketch of some current trends in statistical inference. After an account of the challenges that new forms of data bring, there is a brief overview of some topics in stochastic modelling. The paper then turns to sparsity, illustrated using Bayesian wavelet analysis based on a mixture model and metabolite profiling. Modern likelihood methods including higher order approximation and composite likelihood inference are then discussed, followed by some thoughts on statistical education.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Abramovich F, Sapatinas T and Silverman BW (1998). Wavelet thresholding via a Bayesian approach. J Roy Stat Soc B 60: 725–749

    Article  MathSciNet  MATH  Google Scholar 

  • Ancey C, Davison AC, Böhm T, Jodeau M and Frey P (2008). Entrainment and motion of coarse particles in a shallow water stream down a steep slope. J Fluid Mech 595: 83–114

    Article  MATH  Google Scholar 

  • Azzalini A (1983). Maximum likelihood estimation of order m for stationary stochastic processes. Biometrika 70: 381–387

    Article  MathSciNet  Google Scholar 

  • Barndorff-Nielsen OE and Cox DR (1994). Inference and asymptotics. Chapman & Hall, London

    MATH  Google Scholar 

  • Barndorff-Nielsen OE, Mikosch T and Resnick SI (2001). Lévy processes: theory and applications. Birkhäuser Verlag, Basel

    MATH  Google Scholar 

  • Barndorff-Nielsen OE, Gill RD and Jupp PE (2003). On quantum statistical inference (with discussion). J Roy Stat Soc B 65: 775–816

    Article  MathSciNet  MATH  Google Scholar 

  • Bellio R (1999) Likelihood Asymptotics: Applications in Biostatistics. PhD Thesis, Department of Statistical Science, University of Padova

  • Bellio R and Brazzale AR (1999). On the implementation of approximate conditional inference. Stat Appl 11: 251–271

    Google Scholar 

  • Bellio R and Brazzale AR (2001). A computer algebra package for approximate conditional inference. Stat Comput 11: 17–24

    Article  MathSciNet  Google Scholar 

  • Bellio R and Brazzale AR (2003). Higher-order asymptotics unleashed: Software design for nonlinear heteroscedastic models. J Computat Graphical Stat 12: 682–697

    Article  MathSciNet  Google Scholar 

  • Bhowmick D, Davison AC, Goldstein DR and Ruffieux Y (2006). A Laplace mixture model for the identification of differential expression in microarrays. Biostatistics 7: 630–641

    Article  MATH  Google Scholar 

  • Bickel PJ, Klassen CAJ, Ritov Y and Wellner JA (1993). Efficient and adaptive estimation for semiparametric models. Johns Hopkins University Press, Baltimore

    MATH  Google Scholar 

  • Böhm T, Ancey C, Frey P, Reboud J-L and Ducottet C (2004). Fluctuations of the solid discharge of gravity-driven particle flows in a turbulent stream. Phys Rev E 69: 061307

    Article  Google Scholar 

  • Brazzale AR (1999). Approximate conditional inference in logistic and loglinear models. J Computat Graphical Stat 8: 653–661

    Article  Google Scholar 

  • Brazzale AR (2000) Practical Small-Sample Parametric Inference. PhD Thesis, Department of Mathematics, Swiss Federal Institute of Technology, Lausanne

  • Brazzale AR, Davison AC and Reid N (2007). Applied asymptotics: case studies in small sample statistics. Cambridge University Press, Cambridge

    MATH  Google Scholar 

  • Breiman L (2001). Statistical modeling: the two cultures (with discussion). Stat Sci 16: 199–231

    Article  MathSciNet  MATH  Google Scholar 

  • Bühlmann P, Hothorn T (2006) Boosting algorithms: regularization, prediction and model fitting. http://stat.ethz.ch/buhlmann/bibliog.html.

  • Castillo JD and López-Ratera A (2006). Saddlepoint approximation in exponential models with boundary points. Bernoulli 12: 491–500

    Article  MathSciNet  MATH  Google Scholar 

  • Chellappa R and Jain A (eds) (1993). Markov random fields: theory and application. Academic, New York

    Google Scholar 

  • Clifford P (1990). Markov random fields in statistics. In: Grimmett, GR and Welsh, DJA (eds) Disorder in physical systems: a volume in honour of John M. Hammersley, pp 19–32. Clarendon Press, Oxford

    Google Scholar 

  • Cox DR and Isham VS (1988). A simple spatial-temporal model of rainfall. Proc Roy Soc Lond A 415: 317–328

    Article  MathSciNet  Google Scholar 

  • Cox DR and Reid N (2004). A note on pseudolikelihood constructed from marginal densities. Biometrika 91: 211–221

    Article  MathSciNet  Google Scholar 

  • Davison AC (2003). Statistical models. Cambridge University Press, Cambridge

    MATH  Google Scholar 

  • Donoho DL and Johnstone IM (1994). Ideal spatial adaptation by wavelet shrinkage. Biometrika 81: 425–455

    Article  MathSciNet  MATH  Google Scholar 

  • Efron B (2003). The statistical century. In: Panaretos, J (eds) Stochastic musings: perspectives from the pioneers of the late 20th century, pp 31–46. Laurence Erlbaum, Florence.

    Google Scholar 

  • Efron B, Hastie TJ, Johnstone IM and Tibshirani RJ (2004). Least angle regression (with discussion). Ann Stat 32: 407–499

    Article  MathSciNet  MATH  Google Scholar 

  • Fisher RA (1922). On the mathematical foundations of theoretical statistics. Philos Trans Roy Soc Lond A 222: 309–368

    Article  Google Scholar 

  • Fisher RA (1925). Theory of statistical estimation. Proc Cambridge Philos Soc 22: 700–725

    MATH  Google Scholar 

  • Fisher RA (1934). Two new properties of mathematical likelihood. Proc Roy Soc Lond A 144: 285–307

    Article  MATH  Google Scholar 

  • Freund Y and Schapire RE (1997). A decision-theoretic generalization of on-line learning and an application to boosting. J Comput Syst Sci 55: 119–139

    Article  MathSciNet  MATH  Google Scholar 

  • Gu C (2002). Smoothing spline ANOVA models. Springer, New York

    MATH  Google Scholar 

  • Hall P (2005). On non-parametric statistical methods. In: Davison, AC, Dodge, Y and Wermuth, N (eds) Celebrating statistics: papers in honour of Sir David Cox on his 80th birthday, pp 137–150. Clarendon Press, Oxford.

    Google Scholar 

  • Hand DJ (2006). Classifier technology and the illusion of progress (with discussion). Stat Sci 21: 1–34

    Article  MathSciNet  MATH  Google Scholar 

  • Hastie TJ, Tibshirani RJ and Friedman JH (2001). The elements of statistical learning: data mining, inference, and prediction. Springer, New York

    MATH  Google Scholar 

  • Heard NA, Holmes CC and Stephens DA (2006). A quantitative study of gene regulation involved in the immune response of Anopheline mosquitoes: an application of Bayesian hierarchical clustering of curves. J Am Stat Assoc 101: 18–29

    Article  MathSciNet  MATH  Google Scholar 

  • Isham V (1981). An introduction to spatial point processes and Markov random fields. Int Stat Rev 49: 21–43

    Article  MathSciNet  MATH  Google Scholar 

  • Isham VS (2005). Stochastic models for epidemics. In: Davison, AC, Dodge, Y and Wermuth, N (eds) Celebrating statistics: papers in honour of Sir David Cox on his 80th birthday, pp 27–54. Clarendon Press, Oxford

    Google Scholar 

  • Johnstone IM and Silverman BW (2005). Empirical Bayes selection of wavelet thresholds. Ann Stat 33: 1700–52

    Article  MathSciNet  MATH  Google Scholar 

  • Kou SC, Xie XS and Liu JS (2005). Bayesian analysis of single-molecule experimental data (with discussion). Appl Stat 54: 469–506

    MathSciNet  MATH  Google Scholar 

  • Lau JW, Green PJ (2008) Bayesian model based clustering procedures. Journal of Computational and Graphical Statistics p. (to appear)

  • Lindsay BG (1988). Composite likelihood methods. Contemporary Math 80: 220–241

    MathSciNet  Google Scholar 

  • Lönnstedt I and Speed TP (2002). Replicated microarray data. Stat Sinica 12: 31–46

    MATH  Google Scholar 

  • McCulloch CE and Searle SR (2001). Generalized, linear and mixed models. Wiley, New York

    MATH  Google Scholar 

  • Messerli G, Partovi Nia V, Trevisan M, Kolbe A, Schauer N, Geigenberger P, Chen J, Davison AC, Fernie A and Zeeman SC (2007). Rapid classification of phenotypic mutants of Arabidopsis via metabolite fingerprinting. Plant Physiol 143: 1484–1492

    Article  Google Scholar 

  • Murphy SA and van der Vaart AW (2000). On profile likelihood (with discussion). J Am Stat Assoc 95: 449–485

    Article  MATH  Google Scholar 

  • Owen AB (2001). Empirical likelihood. Chapman & Hall/CRC, Boca Raton

    MATH  Google Scholar 

  • Pace L and Salvan A (1997). Principles of statistical inference from a neo-fisherian perspective. World Scientific, Singapore

    MATH  Google Scholar 

  • Panaretos VM (2006). The diffusion of radon shape. Adv Appl Prob 38: 320–335

    Article  MathSciNet  MATH  Google Scholar 

  • Panaretos VM (2007). Partially observed branching processes for stochastic epidemics. J Math Biol 54: 645–668

    Article  MathSciNet  MATH  Google Scholar 

  • Pearce ND and Wand MP (2006). Penalized splines and reproducing kernel methods. Am Stat 60: 233–240

    Article  MathSciNet  Google Scholar 

  • Porporato A and Rodríguez-Iturbe I (2005). Stochastic soil moisture dynamics and vegetation response. In: Davison, AC, Dodge, Y and Wermuth, N (eds) Celebrating Statistics: papers in honour of Sir David Cox on his 80th birthday, pp 55–72. Clarendon Press, Oxford.

    Google Scholar 

  • Reid N (2003). Asymptotics and the theory of inference. Ann Stat 31: 1695–1731

    Article  MATH  Google Scholar 

  • Rotnitzky A (2005). On semiparametric inference. In: Davison, AC, Dodge, Y and Wermuth, N (eds) Celebrating statistics: papers in honour of Sir David Cox on his 80th birthday, pp 115–136. Clarendon Press, Oxford.

    Google Scholar 

  • Sartori N (2003). Modified profile likelihoods in models with stratum nuisance parameters. Biometrika 90: 533–549

    Article  MathSciNet  Google Scholar 

  • Severini TA (2000). Likelihood methods in statistics. Clarendon Press, Oxford

    MATH  Google Scholar 

  • Tibshirani R (1996). Regression shrinkage and selection via the lasso. J Roy Stat Soc B 58: 267–288

    MathSciNet  MATH  Google Scholar 

  • Varin C (2008) On composite marginal likelihoods. Statistics (to appear)

  • Wahba G (1990). Spline models for observational data. CBMS-NSF regional conference series in applied mathematics. SIAM, Philadelphia

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to A. C. Davison.

Additional information

This paper is based on a lecture given at a ceremony to inaugurate the new building of the Department of Statistics at the Università Ca’ Foscari, Venice, in September 2006. Some of the work described was performed in collaborations with Christophe Ancey, Alessandra Brazzale, Gaëlle Messerli, Vahid Partovi Nia, Nancy Reid and Sam Zeeman. The author thanks members of the Venice department for their generous hospitality and Christophe Ancey, Nicola Sartori, Victor Panaretos, Vahid Partovi Nia and referees for their helpful comments. The work was supported by the Swiss National Science Foundation.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Davison, A.C. Some challenges for statistics. Stat. Meth. & Appl. 17, 167–181 (2008). https://doi.org/10.1007/s10260-007-0079-z

Download citation

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10260-007-0079-z

Keywords

Navigation