Laser treatment of primary axillary hyperhidrosis: a review of the literature
Hyperhidrosis o`ccurs when the body produces sweat beyond what is essential to maintain thermal homeostasis. The condition tends to occur in areas marked by high-eccrine density such as the axillae, palms, and soles and less commonly in the craniofacial area. The current standard of care is topical aluminum chloride hexahydrate antiperspirant (10–20%), but other treatments such as anticholinergics, clonidine, propranolol, antiadrenergics, injections with attenuated botulinum toxin, microwave technology, and surgery have been therapeutically implicated as well. Yet, many of these treatments have limited efficacy, systemic side effects, and may be linked with significant surgical morbidity, creating need for the development of new and effective therapies for controlling excessive sweating. In this literature review, we examined the use of lasers, particularly the Neodynium:Yttrium-Aluminum-Garnet (Nd:YAG) and diode lasers, in treating hyperhidrosis. Due to its demonstrated effectiveness and limited side effect profile, our review suggests that Nd:YAG laser may be a promising treatment modality for hyperhidrosis. Nevertheless, additional large, randomized controlled trials are necessary to confirm the safety and efficacy of this treatment option.
KeywordsHyperhidrosis Diode laser Nd:YAG laser Axilla Sweat glands
We would like to thank Meghan Janette for assisting in data collection for this manuscript.
Compliance with ethical standards
Conflict of interests
The authors declare that they have no conflict of interest.
Ethical approval was not needed for this review.
Informed consent was not needed for this review.
- 5.Schwartz RA (2017) Hyperhidrosis Treatment & Management. In: James WD (ed). Medscape. http://www.emedicine.medscape.com/article/1073359-treatment.. Accessed 15 Dec 2017
- 9.Bechara FG, Georgas D, Sand M, Stucker M, Othlinghaus N, Altmeyer P, Gambichler T (2012) Effects of a long-pulsed 800-nm diode laser on axillary hyperhidrosis: a randomized controlled half-side comparison study. Dermatol Surg 38(5):736–740. https://doi.org/10.1111/j.1524-4725.2012.02339.xCrossRefPubMedGoogle Scholar
- 10.Leclere FM, Moreno-Moraga J, Alcolea JM, Vogt PM, Royo J, Cornejo P, Casoli V, Mordon S, Trelles MA (2015) Efficacy and safety of laser therapy on axillary hyperhidrosis after one year follow-up: a randomized blinded controlled trial. Lasers Surg Med 47(2):173–179. https://doi.org/10.1002/lsm.22324CrossRefPubMedGoogle Scholar