Skip to main content


Log in

Endoscopic lithotripsy for gastric bezoars by Nd:YAG laser-ignited mini-explosive technique

  • Original Article
  • Published:
Lasers in Medical Science Aims and scope Submit manuscript


Until now, there still has no standard treatment option to deal with gastric bezoars. This respective study was conducted to evaluate the safety and efficiency of Nd:YAG laser-ignited mini-explosive technique for the treatment of gastric bezoars. Two hundred sixty patients with 285 gastric bezoars were treated by endoscopic lithotripsy with Nd:YAG laser-ignited mini-explosive technique. Among the 260 patients, the 284 gastric bezoars of the 259 patients completely disappeared, with the cure rate of 99.6 % after 1–2 treatments at 2–4 weeks follow-up. Only one patient, who was cured by surgery, had gastric perforation during the explosion. No intraoperative or delayed complications was found in the other 259 patients. The endoscopic lithotripsy with Nd:YAG laser-ignited mini-explosive technique is an effective, safe, and promising alternative for gastric bezoars.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2

Similar content being viewed by others


  1. Andrus CH, Ponsky JL (1988) Bezoars: classification, pathophysiology, and treatment. Am J Gastroenterol 83:476–478

    CAS  PubMed  Google Scholar 

  2. Blam ME, Lichtenstein GR (2000) A new endoscopic technique for the removal of gastric phytobezoars. Gastrointest Endosc 52:404–408

    Article  CAS  PubMed  Google Scholar 

  3. Muguruma N, Okamura S, Okahisa T, Yasuda M, Hayashi S, Shibata H, Ito S (1998) Electrohydraulic lithotripsy treatment for persimmon bezoars. Endoscopy 30:S60

    Article  CAS  PubMed  Google Scholar 

  4. Rinetti M, Bianchi G, Monfrino G, Prever F, Zinelli LC (1980) Enzyme dissolution of a phytobezoar in a gastreetomized subject. Endoscopy 12:90–93

    Article  CAS  PubMed  Google Scholar 

  5. Ladas SD, Kamberoglou D, Karamanolis G, Vlachogiannakos J, Zouboulis-Vafiadis I (2013) Systematic review: Coca-Cola can effectively dissolve gastric phytobezoars as a first-line treatment. Aliment Pharmacol Ther 37:169–173

    Article  CAS  PubMed  Google Scholar 

  6. Walker-Renard P (1993) Update on the medical management of phytobezoars. Am J Gastroenterol 88:1663–1666

    CAS  PubMed  Google Scholar 

  7. Koulas SG, Zikos N, Charalampous C, Christodoulou K, Sakkas L, Katsamakis N (2008) Management of gastrointestinal bezoars: an analysis of 23 cases. Int Surg 93:95–98

    CAS  PubMed  Google Scholar 

  8. Huang YC, Guo ZH, Gu Y, Yang JQ, Liu QC, Cheng GY, Chen HL (1990) Endoscopic lithotripsy of gastric bezoars using a laser-ignited mini-explosive device. Chin Med J (Engl) 103:152–155

    CAS  Google Scholar 

  9. Mao YP (2007) Diagnosis and treatment of gastric bezoars. Zhongguo Xiaohua Neijing 1:42–44

    Google Scholar 

  10. Robles R, Parrilla P, Escamilla C, Lujan JA, Torralba JA, Liron R, Moreno A (1994) Gastrointestinal bezoars. Br J Surg 81:1000–1001

    Article  CAS  PubMed  Google Scholar 

  11. Madsen R, Skibba RM, Galvan A, Striplin C, Scott P (1978) Gastric bezoars. A technique of endoscopic removal. Am J Dig Dis 23:717–719

    Article  CAS  PubMed  Google Scholar 

  12. Van Gossum A, Delhaye M, Cremer M (1989) Failure of non-surgical procedures to treat gastric trichobezoar. Endoscopy 21:113

    Article  PubMed  Google Scholar 

  13. Azevedo S, Lopes J, Marques A, Mourato P, Freitas L, Lopes AI (2011) Successful endoscopic resolution of a large gastric bezoar in a child. World J Gastrointest Endosc 3:129–132

    Article  PubMed Central  PubMed  Google Scholar 

  14. Sharma D, Srivastava M, Babu R, Anand R, Rohtagi A, Thomas S (2010) Laparoscopic treatment of gastric bezoar. JSLS 14:263–267

    Article  PubMed Central  PubMed  Google Scholar 

  15. Erzurumlu K, Malazgire Z, Bektas A, Dervisoglu A, Polat C, Senyurek G, Yetim I, Ozkan K (2005) Gastrointestinal bezoars: a retrospective analysis of 34 cases. World J Gastroenterol 11:1813–1817

    PubMed  Google Scholar 

  16. Bruzzese A, Chiarini S, Marchegiani C, Corbellini L, Stella S (1997) Endoscopic fragmentation of gastric phytobezoars as a valid alternative, in selected cases, to traditional surgery. G Chir 18:485–487

    CAS  PubMed  Google Scholar 

  17. Kumar P, Misra NC, Jaiswal MS, Singh AK, Chaturevedi A (1987) Phytobezoar with gastric ulcer. Indian J Gastroenterol 6:248

    CAS  PubMed  Google Scholar 

Download references


This work was supported by the Beijing Municipal Natural Science Foundation (no. 4122090).

Author information

Authors and Affiliations


Corresponding author

Correspondence to Yongping Mao.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Mao, Y., Qiu, H., Liu, Q. et al. Endoscopic lithotripsy for gastric bezoars by Nd:YAG laser-ignited mini-explosive technique. Lasers Med Sci 29, 1237–1240 (2014).

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: