Infection caused by Sporothrix schenckii: an autochthonous case in Bari, Southern Italy

Abstract

An autochthonous case of lymphocutaneous sporotrichosis caused by Sporothrix schenckii is reported. The patient developed skin lesions localized along the lymphatics that appeared after he suffered an injury while collecting wicker canes in marshy water. The fungus was identified as Sporothrix schenckii by MALDI-TOF and sequencing. Phylogenetic analysis was also performed. Low MIC values were detected for all tested echinocandins and azoles except for fluconazole. The patient was treated with itraconazole without significant improvement. A regression of lesions was observed after 3 months of therapy with voriconazole. Few cases of sporotrichosis have been reported in Europe. However, several cases of sporotrichosis have been described in Italy. The incidence of sporotrichosis in Italy may be underestimated and microbiologists, and clinicians must be aware of this fungal infection.

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Availability of data and material

The isolated strain of S. schenckii is available for authors having scientific interest.

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Correspondence to Rosa Monno.

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The study did not require approval from the ethics committee, according to the Italian law, since it was performed in the context of normal clinical routines (Art. 1, Leg. Decree 211/2003). However, all patients referring to our institute provided consent for the use of their data for research purposes. In any case, data were previously anonymized, according to the requirements set by Italian Data Protection Code (Leg. Decree 196/2003).

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Monno, R., Brindicci, G., Romeo, O. et al. Infection caused by Sporothrix schenckii: an autochthonous case in Bari, Southern Italy. Eur J Clin Microbiol Infect Dis (2020). https://doi.org/10.1007/s10096-020-03939-z

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Keywords

  • Sporotrichosis
  • Lymphocutaneous lesions
  • Voriconazole