Background and aims
Stroke is a leading cause of death and disability worldwide. However, our knowledge of the incidence of stroke for Saudi Arabian population is not known. Thus, we aimed to determine the pooled annual incidence of stroke in Saudi Arabia.
Summary of review
We conducted a comprehensive literature search of PubMed, Web of Science, and SCOPUS, without language or publication year limits. Outcomes of interest were stroke incidence rate for both first and recurrent. A total of five studies met the inclusion criteria for this review. The pooled annual incidence of stroke in Saudi Arabia was 0.029% (95% CI: 0.015 to 0.047) equivalent of 29 strokes per 100,000 people annually (95% CI: 15 to 47).
The findings indicate that there are 29 stroke cases for every 100,000 people annually for individuals residing Saudi Arabia. Our values were lower than those of other high-income countries. Establishing a nationwide stroke registry is warranted for monitoring and improving healthcare services provided to stroke survivors.
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Mendis S, Puska P, Norrving B (2011) Global atlas on cardiovascular disease prevention and control. World Health Organ:2–14
Aho K, Harmsen P, Hatano S, Marquardsen J, Smirnov VE, Strasser T (1980) Cerebrovascular disease in the community: results of a WHO collaborative study. Bull World Health Organ 58(1):113–130
Benjamin EJ, Blaha MJ, Chiuve SE, Cushman M, Das SR, Deo R et al Heart Disease and Stroke Statistics 2017 At-a-Glance. Circulation. 2017:1–5
Morse A. Department of Health: Progress in improving stroke care. Natl Audit Off Rep. 2010;(February)
Tran J, Mirzaei M, Anderson L, Leeder SR (2010) The epidemiology of stroke in the Middle East and North Africa. J Neurol Sci 295(1–2):38–40
al Rajeh S, Awada A, Niazi G, Larbi E (1993) Stroke in a Saudi Arabian National Guard Community: analysis of 500 consecutive cases from a population-based hospital. Stroke. 24(11):1635–1639
Ayoola AE, Banzal SS, Elamin AK, Gadour MO, Elsammani EW, Al-Hazmi MH (2003) Profile of stroke in Gizan, Kingdom of Saudi Arabia. Neurosciences 8(4):229–232
Almekhlafi MA (2016) Trends in one-year mortality for stroke in a tertiary academic center in Saudi Arabia: a 5-year retrospective analysis. Ann Saudi Med 36(3):197–202
Moher D, Liberati A, Tetzlaff J, Altman DG, Altman D, Antes G et al (2009) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement (Chinese edition). J Chin Integr Med 7:889–896
Wells GA O’Connell D. B Shea. The Newcastle-Scale for assessing the quality of nonrandomised studies in meta-analyses. Ottawa Ottawa Hosp Res Inst. 2011;
Lipsey MW, Wilson DB (2001) Practical meta-analysis. Appl Soc Res Methods Ser 49:264
Barendregt JJ, Doi SA, Lee YY, Norman RE, Vos T (2013) Meta-analysis of prevalence. J Epidemiol Community Health 67(11):974–978
(2019) R: A Language and Environment for Statistical Computing. Vienna, Austria: R Foundation for Statistical Computing
Al-Shenqiti AM, Ibrahim SR, Khaled OA, Ali ARH, Ahmed MS (2017) Incidence of first time stroke: a Saudi experience. Eur Neurol 77(3–4):147–151
Al-Rajeh S, Larbi EB, Bademosi O, Awada A, Yousef A, Al-Freihi H et al (1998) Stroke register: experience from the Eastern Province of Saudi Arabia. Cerebrovasc Dis 8(2):86–89
Alhazzani AA, Mahfouz AA, Abolyazid AY, Awadalla NJ, Aftab R, Faraheen A et al (2018) Study of stroke incidence in the aseer region, southwestern Saudi Arabia. Int J Environ Res Public Health (2):15
Al-Sulaiman A, Bademosi O, Ismail H, Magboll G (1999) Stroke in Saudi children. J Child Neurol 14(5):295–298
GBD 2016 Stroke Collaborators (2019) Global, regional, and national burden of stroke, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurol 18(5):439–458. https://doi.org/10.1016/S1474-4422(19)30034-1
Giampaoli S, Hammar N, Adany R, De Peretti C (2007) Population-based register of stroke: manual of operations. Eur J Cardiovasc Prev Rehabil 14(SUPPL. 3)
Béjot Y, Bailly H, Durier J, Giroud M (2016) Epidemiology of stroke in Europe and trends for the 21st century. Presse Medicale 45:e391–e398
Cushman M, Cantrell RA, McClure LA et al (2008) Estimated 10-year stroke risk by region and race in the United States: geographic and racial differences in stroke risk. Ann Neurol 64(5):507–513. https://doi.org/10.1002/ana.21493
Connor M (2004) Prevalence of stroke survivors in rural South Africa: results from the Southern Africa Stroke Prevention Initiative (SASPI) Agincourt Field Site. Stroke. 35(3):627–632
Kulshreshtha A, Anderson LM, Goyal A, Keenan NL (2012) Stroke in South Asia: a systematic review of epidemiologic literature from 1980 to 2010. Neuroepidemiology 38:123–129
Feigin VL, Forouzanfar MH, Krishnamurthi R, Mensah GA, Connor M, Bennett DA, Moran AE, Sacco RL, Anderson L, Truelsen T, O'Donnell M, Venketasubramanian N, Barker-Collo S, Lawes CMM, Wang W, Shinohara Y, Witt E, Ezzati M, Naghavi M, Murray C (2014) Global and regional burden of stroke during 1990-2010: findings from the global burden of disease study 2010. Lancet. 383(9913):245–255
Doi SAR, Barendregt JJ, Khan S, Thalib L, Williams GM (2015) Advances in the meta-analysis of heterogeneous clinical trials I: the inverse variance heterogeneity model. Contemp Clin Trials 45:130–138
Euser AM, Zoccali C, Jager KJ, Dekker FW (2009) Cohort studies: prospective versus retrospective. Nephron Clin Pract 113
This study was supported by the deanship of scientific research at Prince Sattam bin Abdulaziz University under the project # 2019/03/10805.
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Alqahtani, B.A., Alenazi, A.M., Hoover, J.C. et al. Incidence of stroke among Saudi population: a systematic review and meta-analysis. Neurol Sci (2020). https://doi.org/10.1007/s10072-020-04520-4
- Systematic review