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Quality of life assessment in migraine and relapsing remitting multiple sclerosis: self-perceived health is similar

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Abstract

Objective

The aim of this study was to compare self-perceived health between migraine and early stages of relapsing-remitting multiple sclerosis (RRMS) and to explore whether and how accurate those health domains predict overall quality of life.

Methods

Ninety patients aged 18–55 years were enrolled in this cross-sectional study. Thirty follow-up outpatients were recruited with migraine (with or without aura), 30 patients with RRMS, and 30 healthy subjects. They were asked to complete the Health status questionnaire (SF-36) and Personal Wellbeing Index (PWI).

Results

Patients with RRMS and migraine had significantly worse self-reported health regarding role limitation due to physical problems and general health than the healthy control group. Additionally, migraine patients had more bodily pain, while RRMS patients expressed more difficulties regarding physical functioning. Differences between migraine and RRMS patients were not significant. Hierarchical regression analysis revealed that role limitation due to physical problems, mental health, and general health represents significant predictors of overall quality of life.

Conclusions

Migraine may affect quality of life similarly to early stages of RRMS. Bio-psycho-socio-medical understanding of the two diseases and their impact on patients QoL should be reconsidered.

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Acknowledgements

The authors thank Prof. Claudio Baracchini, MD, Head of Stroke Unit and Neurosonology Lab, Department of Neuroscience, University of Padua School of Medicine, Padua, Italy. Iva Vranić, mag. psych. Josipa Erdeši, mag. psych.

Author information

Authors and Affiliations

  1. Department of Neurology, General Hospital Zadar, Bože Peričića 5, Zadar, Croatia

    Klaudia Duka Glavor & Anamarija Mrđen

  2. Department of Health Studies, University of Zadar, Zadar, Croatia

    Klaudia Duka Glavor & Anamarija Mrđen

  3. Department of Neurology, University Hospital Centre Split, Split, Croatia

    Marina Titlić

  4. School of Medicine, University of Split, Split, Croatia

    Marina Titlić & Marina Maras Šimunić

  5. Department of Psychology, Faculty of Humanities and Social Science in Osijek, J. J. Strossmayer University of Osijek, Osijek, Croatia

    Gorka Vuletić

  6. A. Stampar School of Public Health, School of Medicine University of Zagreb, Zagreb, Croatia

    Gorka Vuletić

  7. Department of Radiology, University Hospital Centre Split, Split, Croatia

    Marina Maras Šimunić

Authors
  1. Klaudia Duka Glavor
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  2. Marina Titlić
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  3. Gorka Vuletić
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  4. Anamarija Mrđen
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  5. Marina Maras Šimunić
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Contributions

Klaudia Duka Glavor study design of the article, data collection, literature searches, writing the manuscript, approval of the final version.

Marina Titlić study design, supervisior of the research, approval of the final version.

Gorka Vuletić study design, statistical analysis and interpretation of results, approval of the final version.

Anamarija Mrđen study design (sample), interpretation of the results, comments on the draft paper.

Marina Maras Šimunić study design, literature searches, comments on the draft paper.

Corresponding author

Correspondence to Klaudia Duka Glavor.

Ethics declarations

The study protocol was approved by the local Ethics Committee and all participants signed a written informedconsent. The study was conducted in accordance with the World Medical Association Declaration of Helsinki.

Conflict of interest

The authors declare that they have no conflict of interest.

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Glavor, K.D., Titlić, M., Vuletić, G. et al. Quality of life assessment in migraine and relapsing remitting multiple sclerosis: self-perceived health is similar. Neurol Sci 40, 2549–2554 (2019). https://doi.org/10.1007/s10072-019-04005-z

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  • DOI: https://doi.org/10.1007/s10072-019-04005-z

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