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Neurological Sciences

, Volume 39, Issue 5, pp 835–839 | Cite as

Relevance of sleep quality on caregiver burden in Parkinson’s disease

  • Luigi Bartolomei
  • Andrea Pastore
  • Lucia Meligrana
  • Elena Sanson
  • Nicola Bonetto
  • Giacomo Maria Minicuci
  • Sandro Zambito Marsala
  • Tiziana Mesiano
  • Lorenzo Bragagnolo
  • Angelo Antonini
Original Article

Abstract

Parkinson’s disease (PD) is a neurodegenerative disorder which affects the quality of life of patient and their family. Sleep disorders appear in 80–90% of PD patients and have a great impact on the PD well-being. We examined the relationship of patients’ sleep quality and depression on burden, mood, quality of life, and quality of sleep of their caregivers. A multicenter, regional (Veneto), observational, cross-sectional study that included 55 patient-caregiver pairs was conducted. Patients were assessed using Parkinson’s Disease Sleep Scale (PDSS) and Epworth Sleepiness Scale (ESS) for sleep disorders, Beck Depression Inventory (BDI) as a measure of depression, and Parkinson’s Disease Questionnaire (PDQ-39) as a measure of quality of life. Caregivers were evaluated by the Caregiver Burden Inventory (CBI) a measure of burden, BDI, SF-36 Health Survey as measures of HRQoL, and Medical Outcomes Study-Sleep Scale (MOS-SS) for quality of sleep. CBI, HRQoL, MOS-SS, and BDI scores displayed no association with patients’ age, cognition (Mini Mental State Examination (MMSE) and Frontal Assessment Battery (FAB)), disease duration, and Hoehn and Yahr (H&Y), and UPDRS III scales whereas were significantly correlated with patients’ quality of sleep, depression, and quality life. CBI and HRQoL were also associated respectively with patients’ ESS and l-dopa daily dose. This study underscores the presence of a significant relationship between patient and caregiver quality of life. Interestingly, sleep quality and depression rather than motor disability best predicted caregivers’ well-being

Keywords

Sleep disturbance Burden caregiver Quality of life Depression Parkinson’s disease 

Notes

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Research involving human participants

All procedures performed in this study were in accordance with the ethical standards of the institutional research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.

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Copyright information

© Springer-Verlag Italia S.r.l., part of Springer Nature 2018

Authors and Affiliations

  • Luigi Bartolomei
    • 1
    • 2
  • Andrea Pastore
    • 3
  • Lucia Meligrana
    • 1
    • 4
  • Elena Sanson
    • 1
    • 4
  • Nicola Bonetto
    • 1
  • Giacomo Maria Minicuci
    • 1
  • Sandro Zambito Marsala
    • 5
  • Tiziana Mesiano
    • 6
  • Lorenzo Bragagnolo
    • 7
  • Angelo Antonini
    • 8
    • 9
  1. 1.Department of NeurosciencesSan Bortolo HospitalVicenzaItaly
  2. 2.U.O. NeurologiaOspedale San BortoloVicenzaItaly
  3. 3.Department of EconomicsCa’ Foscari UniversityVeniceItaly
  4. 4.Psychology UnitSan Bortolo HospitalVicenzaItaly
  5. 5.Neurology DepartmentSan Martino HospitalBellunoItaly
  6. 6.Neurology DepartmentCazzavillan HospitalArzignanoItaly
  7. 7.Neurology DepartmentSan Bassiano HospitalBassanoItaly
  8. 8.Parkinson and Movement Disorders UnitFondazione Ospedale San Camillo “I.R.C.C.S.”VeniceItaly
  9. 9.Department of Neurosciences (DNS)Padova UniversityPadovaItaly

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