Transient lesion in splenium of the corpus callosum presenting as mild encephalopathy
Acquired lesions in splenium of the corpus callosum (SCC) in magnetic resonance imaging (MRI) can be seen in several various disorders, including ischemia, demyelinating disorders, tumours and trauma . It is reported with approximately 3% prevalence in a large number of patients by McLeod et al. The development of radiological technology and the increased accessibility of advanced MRI techniques such as diffusion-weighted MRI (DWI) have resulted in the detection of transient lesions in SCC in recent years. As those lesions have been reported in patients with mild encephalopathy/encephalitis, it is called as mild encephalopathy with reversible isolated SCC lesion (MERS) .
A 45-year-old female was admitted to the psychiatry department of the hospital 15 days prior by depressive mood, scepticism and decreased speech after a discussion with her husband. She was diagnosed as having psychotic depression and prescribed olanzapine and citalopram. Although she used the...
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Conflict of interest
The authors declare that they have no conflict of interest.