Epilepsy caused by superficial hemosiderosis of the central nervous system
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Superficial hemosiderosis of the central nervous system (CNS) is an uncommon and often unrecognized disorder caused by small repeated hemorrhages into the subarachnoid space, resulting in CNS hemosiderin deposition in the subpial layers. The etiology is reported to be idiopathic in 35% of cases, CNS tumor in 15%, trauma in 13%, and arteriovenous malformation in 9% of cases. It is rarely caused by intradural neurosurgical operations, nerve root avulsion, or other causes of subarachnoid hemorrhage . Xanthochromia is a common finding. Also, magnetic resonance imaging (MRI) of the CNS reveals a rim of hypointensity on T2-weighted images involving the surface of the brainstem, cerebellum, and cortical fissures. The classical symptoms include sensorineural hearing impairment, visual impairment, slowly progressing cerebellar ataxia, and pyramidal signs, but this syndrome rarely clinically presents with seizures. To date, there are only few reported cases of seizures...
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The authors declare that they have no conflict of interest.
This article does not contain any studies with human participants performed by any of the authors.
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