Abstract
We present two Parkinson’s disease (PD) patients, who experienced heatstroke. Both patients manifested central nervous system dysfunction with elevated core temperature. Despite adequate lowering of the body temperature, multiorgan-dysfunction syndrome including encephalopathy, rhabdomyolysis, acute renal failure, acute respiratory failure, and disseminated intravascular coagulopathy was noted in one patient, leading to permanent neurologic damage. Because the ensuing multiorgan dysfunction could determine the functional prognosis in heatstroke patients, it is important to provide information about the prevention of heatstroke to patients, who are isolated or are severely disabled in the advanced stages of PD.
Similar content being viewed by others
References
Bouchama A, Knochel JP (2002) Heat stroke. N Engl J Med 346:1978–1988
Dematte JE, O’Mara K, Buescher J et al (1998) Near-fatal heat stroke during the 1995 heat wave in Chicago. Ann Intern Med 129:173–181
Hoehn MM, Yahr MD (1967) Parkinsonism: onset, progression and mortality. Neurology 17:427–442
Litman RE (1952) Heatstroke in parkinsonism. AMA Arch Intern Med 89:562–567
Hirayama M (2006) Sweating dysfunctions in Parkinson’s disease. J Neurol 253(Suppl 7):VII42–VII47
Yoshioka M, Oka H, Morita M, Inoue K (2003) Sudomotor dysfunction in Parkinson’s disease. Rinsho Shinkeigaku 43:379–384
Kihara M, Kihara Y, Tukamoto T et al (1993) Assessment of sudomotor dysfunction in early Parkinson’s disease. Eur Neurol 33:363–365
Saito H, Kogure K (1989) Thermal sudomotor deficits in Parkinson’s disease. Rinsho Shinkeigaku 29:734–740
Takubo H, Harada T, Hashimoto T et al (2003) A collaborative study on the malignant syndrome in Parkinson’s disease and related disorders. Parkinsonism Relat Disord 9(Suppl 1):S31–S41
Onofrj M, Thomas A (2005) Acute akinesia in Parkinson disease. Neurology 64:1162–1169
Acknowledgments
This work was partly supported by Grants-in-Aid from the Research Committee of CNS Degenerative Disease, the Ministry of Health, Labour and Welfare of Japan.
Conflict of interest
The authors certify that there is no current or potential conflict of interest in relation to this article.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Yamashita, S., Uchida, Y., Kojima, S. et al. Heatstroke in patients with Parkinson’s disease. Neurol Sci 33, 685–687 (2012). https://doi.org/10.1007/s10072-011-0842-7
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s10072-011-0842-7