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RETRACTED ARTICLE: Cognitive deficits in multiple sclerosis: a review of functional MRI studies

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This article was retracted on 15 February 2012

Abstract

Cognitive dysfunction frequently occurs during the course of multiple sclerosis (MS). In patients with MS the severity of cognitive manifestations is not closely related to indices of structural brain damage. Neuroplasticity may contribute to the maintenance of normal performance despite scattered brain lesions. Changes in functional organization of the cerebral cortex have been reported by functional magnetic resonance imaging (fMRI) studies in MS. fMRI studies provide an interesting way of understanding how the brain changes its functional organization in response to MS, and might be useful in the study of the effects of rehabilitative or pharmacological therapy on brain plasticity. The purpose of this review is to examine major fMRI studies focusing on cognitive dysfunction in MS.

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Conflict of interest

C. Pozzilli received honoraria for consultancy or speaking from Sanofi Aventis, Biogen, Bayer schering, Merck Serono and Novartis and received research grants from Sanofi Aventis, Merck Serono and Bayer Schering. E. Tinelli, F. Caramia and A. Francia declare that they have no conflict of interest related to the publication of this article.

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Authors and Affiliations

  1. Department of Neurological Sciences, University of Rome “La Sapienza”, Viale dell’Università 30, 00185, Rome, Italy

    Francesca Caramia, E. Tinelli, A. Francia & C. Pozzilli

Authors
  1. Francesca Caramia
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  2. E. Tinelli
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  3. A. Francia
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  4. C. Pozzilli
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Corresponding author

Correspondence to Francesca Caramia.

Additional information

This article has been retracted upon request of the editor since significant portions of the article were published earlier in another article.

An erratum to this article can be found online at http://dx.doi.org/10.1007/s10072-012-0983-3.

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Caramia, F., Tinelli, E., Francia, A. et al. RETRACTED ARTICLE: Cognitive deficits in multiple sclerosis: a review of functional MRI studies. Neurol Sci 31 (Suppl 2), 239–243 (2010). https://doi.org/10.1007/s10072-010-0379-1

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  • DOI: https://doi.org/10.1007/s10072-010-0379-1

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