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Central sleep apnoea in Rett syndrome

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Abstract

Breathing disturbances in Rett syndrome were reported almost entirely during wakefulness, with normal respiration during sleep. We studied a case of a proven MECP2 mutation in a girl, whose videopolygraphic and polysomnographic monitoring suggested the evidence of central apnoeas not only during awake, but also during sleep. Apart from prevalent awake respiratory dysfunction, central apnoeas in Rett syndrome may be also present during sleep.

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Authors and Affiliations

  1. Epilepsy Center, Neurological Unit, Casa Divina Provvidenza, Opera Don Uva, Via Bovio 78, 70052, Bisceglie (BAT), Italy

    Giuseppe d’Orsi, Vincenzo Demaio & Mauro G. Minervini

  2. Pneumologic Rehabilitation, Casa Divina Provvidenza, Opera Don Uva, Bisceglie (BAT), Italy

    Francesco Scarpelli

  3. Neurological Rehabilitation, “Quarto di Palo”, Andria (BAT), Italy

    Teresa Calvario

Authors
  1. Giuseppe d’Orsi
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  2. Vincenzo Demaio
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  3. Francesco Scarpelli
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  4. Teresa Calvario
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  5. Mauro G. Minervini
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Correspondence to Giuseppe d’Orsi.

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d’Orsi, G., Demaio, V., Scarpelli, F. et al. Central sleep apnoea in Rett syndrome. Neurol Sci 30, 389–391 (2009). https://doi.org/10.1007/s10072-009-0108-9

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  • DOI: https://doi.org/10.1007/s10072-009-0108-9

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