Association of tooth agenesis with dental anomalies in young subjects



The aim of the current study is to correlate the presence of tooth agenesis with other dental anomalies in 7- to 15-year-old patients.

Materials and methods

After evaluating 4000 panoramic radiographs of young subjects, 430 revealed the presence of tooth agenesis, except for the third molar, and are retrospectively observed and compared with a non-agenesis control group of 500 subjects, in order to investigate the existence of other associated dental anomalies in both groups.


The prevalence of tooth agenesis was approximately 9.30% (430/4000); no significant gender differences were found. A significantly higher prevalence of microdontia of the maxillary lateral incisors (p < 0.001) and delayed tooth development (p = 0.0001) was observed in the agenesis group (group A), while delayed development of permanent teeth (p < 0.0001) and hypo-occlusion of the primary molars (p = 0.0130) were found in the control group (group B).


Agenesis patients presented a significantly higher prevalence of microdontia of the maxillary lateral incisors. Instead, non-agenesis patients presented a high prevalence of delayed permanent tooth development and hypo-occlusion of the primary molars. Moreover, further researches are needed to elucidate the role of genetics and environmental factors in the current sample group.

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Correspondence to Paola Martina Marra.

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Marra, P.M., Iorio, B., Itro, A. et al. Association of tooth agenesis with dental anomalies in young subjects. Oral Maxillofac Surg 25, 35–39 (2021).

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  • Dental anomalies
  • Panoramic radiograph
  • Tooth agenesis