Crestal bone response to loaded zirconia and titanium implants: a radiographic and histometric analysis in canines

Abstract

Objectives

To evaluate the crestal bone response to a two-piece zirconia implant compared with a control titanium implant using periapical radiographs (PAs) and histometry.

Materials and methods

Thirty zirconia and 30 titanium implants were placed in healed posterior mandibles of five canines. Full-ceramic single-tooth restorations were cemented after 6 weeks of healing. Three observers measured the distance between the implant shoulder and the crestal bone (DIB) at placement, loading, and harvesting after 4 or 16 weeks in function. The influence of implant material and loading time on DIB as well as the inter-observer agreement were analyzed. Additionally, histometric distance between implant shoulder and most coronal bone-to-implant contact (IS-cBIC) was compared with DIB.

Results

Mean DIB values increased between 4 and 16 weeks of loading for both zirconia (from 1.66 to 2.25 mm; P < 0.0001) and titanium (from 1.81 to 1.95 mm; P = 0.06). Zirconia yielded mean IS-cBIC values of 2.18 mm and 2.48 mm (P < 0.001) and titanium 2.23 mm and 2.34 mm (P = 0.27) after 4 and 16 weeks, respectively. The raters reached an excellent intraclass correlation coefficient. PAs underestimated the bone loss on average by 0.39 mm.

Conclusions

Zirconia implants showed a greater increase of DIB during early healing and function than titanium.

Clinical relevance

Crestal peri-implant tissue dimensions may show more pronounced changes around two-piece zirconia implants during early healing. PAs may underestimate peri-implant bone loss.

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Acknowledgments

The authors gratefully acknowledge the support of Ms. Sonja Bustamante, Dr. Archie A. Jones, and Ms. Linda Torres, Department of Periodontics; and of the team at the Department of Laboratory Animals Resources, University of Texas Health Science Center at San Antonio. The accurate histologic preparation and analysis performed by Mr. David Reist, Ms. Silvia Owusu, and Ms. Margrit Rüfenacht at Robert K. Schenk Laboratory of Oral Histology, School of Dental Medicine, University of Bern; and Prof. Dr. S. Milz and his team at Anatomische Anstalt Munich are highly appreciated. The authors also thank Dr. G. Raeber and Dr. M. Obrecht (Institut Straumann AG) for providing expertise and support during the study and Ms. Jennifer Hockley for the language editing of the manuscript.

Funding

This study was funded with a research grant from the International Team for Implantology, Basel, Switzerland (ITI Grant No. 858_2012). The study materials were kindly provided by Institut Straumann AG, Basel.

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Correspondence to Simone F. M. Janner.

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All applicable international, national, and/or institutional guidelines for the care and use of animals were followed. The study was conducted in accordance with the ethical standards of current US federal regulations. The University of Texas Health Science Center at San Antonio Institutional Animal Care and Use Committee approved animal selection, management, and study protocol prior to the start of the experiment (IACUC; ID no. 13005x).

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Oeschger, C.E., Bosshardt, D.D., Roehling, S. et al. Crestal bone response to loaded zirconia and titanium implants: a radiographic and histometric analysis in canines. Clin Oral Invest 24, 3609–3617 (2020). https://doi.org/10.1007/s00784-020-03235-2

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Keywords

  • Crestal bone
  • Dental implants
  • Osseointegration
  • Radiographic analysis
  • Zirconia implants