Oral health-related quality of life changes in children following dental treatment under general anaesthesia: a meta-analysis
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To conduct a meta-analysis of studies that have employed the Early Childhood Oral Health Impact Scale (ECOHIS) and Child Oral Health-Related Quality of Life (COHRQoL) instruments, to evaluate the oral health-related quality of life (OHRQoL) changes in children following dental treatment under general anaesthesia (DGA).
A systematic search of 5 databases was conducted in accordance with the PRISMA guidelines. The inclusion criteria were use of ECOHIS and COHRQoL, pre-and post-operative assessments, patients aged between 0 and 16 years, no restrictions on the follow-up period and DGA. The primary outcome measure was changes in quality of life for both the children, which was based on mean difference (MD). Twenty-two articles were included in the meta-analysis.
A favourable outcome in OHRQoL was identified in all studies. The combined MD for ECOHIS and COHRQoL were 1.62 [95% CI 1.52–1.71; P < 0.00001; I2 = 0%] and 0.86 [95% CI 0.74–0.99; P < 0.00001; I2 = 0%], respectively, both with no evidence of heterogeneity.
There is evidence to support that the OHRQoL of children was improved, with large effect size, in the short-term following DGA.
Dental treatment under GA significantly improved the OHRQoL of children.
KeywordsChildren Dental treatment Impact General anaesthesia Quality of life
The authors would like to acknowledge Dr. Matthew Payne for his assistance.
Compliance with ethical standards
Conflict of interest
The authors declare that there they have no conflict of interest.
This article does not contain any studies with human participants or animals performed by any of the authors.
For this type of study, formal consent is not required.
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