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Laborüberdiagnostik und iatrogene Anämie

Bausteine eines erfolgreichen Patient-Blood-Management-Konzepts

Laboratory Overdiagnosis and Iatrogenic Anemia

Building Blocks for a Successful Patient Blood Management Concept

  • Anästhesie & Intensivmedizin
  • Published:
Wiener klinisches Magazin Aims and scope

Zusammenfassung

Etwa 50–90 % aller Patienten im Krankenhaus entwickeln eine Anämie. Obwohl die zugrunde liegenden Ursachen zumeist komplex sind, wird insbesondere der Einfluss medizinischer Blutentnahmen im Rahmen der Behandlung unterschätzt. Die hierdurch erzeugte oder zumindest unterhaltene Anämie kann größtenteils durch ein Maßnahmenbündel aus korrekt indizierter Blutentnahmefrequenz, der Verwendung minimierter Blutentnahmeröhrchen sowie der Optimierung des Blutverwurfs entscheidend reduziert werden. Diese Techniken stellen weitere Bausteine eines erfolgreichen Patient-Blood-Management-Konzepts dar.

Abstract

About 50 to 90% of inhospital patients develop anemia. Underlying causes remain complex, but especially the role of phlebotomy induced blood loss has been underestimated, yet. The so caused or aggravated anemia can be modified by implementing a bundle of measures including correct indications of blood drawing frequencies, usage of minimized blood collector tubes and optimization of discarded blood. These techniques are further parts of a successful Patient Blood Management concept.

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Authors and Affiliations

  1. Klinik für Anästhesiologie, Intensivmedizin und Schmerztherapie, Universitätsklinikum Frankfurt, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Deutschland

    Holger Neb,  Leonie Judd,  Kai Zacharowski &  Patrick Meybohm

  2. Central Laboratory, University Hospital Frankfurt am Main, Theodor-Stern-Kai 7, Frankfurt am Main, Deutschland

    Gudrun Hintereder

Authors
  1. Holger Neb
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  2. Leonie Judd
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  3. Gudrun Hintereder
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  4. Kai Zacharowski
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  5. Patrick Meybohm
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Corresponding author

Correspondence to Holger Neb.

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Interessenkonflikt

K. Zacharowski department is receiving unrestricted educational grants from B. Braun Melsungen AG, Fresenius Kabi GmbH, CSL Behring GmbH and Vifor Pharma GmbH. In the past 3 years, K. Zacharowski has received honoraria or travel support for consulting or lecturing from the following companies: Abbott GmbH &Co KG, AesculapAkademie GmbH, AQAI GmbH, AstellasPharma GmbH, AstraZeneca GmbH, Aventis Pharma GmbH, B. Braun Melsungen AG, Baxter Deutschland GmbH, Biosyn GmbH, Biotest AG, Bristol-Myers Squibb GmbH, CSL Behring GmbH, Dr. F. KöhlerChemie GmbH, Dräger Medical GmbH, Essex Pharma GmbH, Fresenius Kabi GmbH, Fresenius Medical Care, Gambro Hospal GmbH, Gilead, GlaxoSmithKline GmbH, Grünenthal GmbH, Hamilton Medical AG, HCCM Consulting GmbH, Heinen+Löwenstein GmbH, Janssen-Cilag GmbH, med Update GmbH, Medivance EU B.V., MSD Sharp&Dohme GmbH, Novartis Pharma GmbH, Novo Nordisk Pharma GmbH, P. J. Dahlhausen&Co. GmbH, Pfizer Pharma GmbH, Pulsion Medical Systems S.E., Siemens Healthcare, Teflex Medical GmbH, Teva GmbH, TopMedMedizintechnik GmbH, Verathon Medical, ViforPharma GmbH. P. Meybohm received research grants from the German Research Foundation (ME 3559/1-1, ME 3559/3-1), International Anesthesia Research Society, German Society of Anaesthesiology and Intensive Care Medicine, European Society of Anaesthesiology, grants by B. Braun Melsungen, CSL Behring, Fresenius Kabi and Vifor Pharma for the implementation of Frankfurt‘s Patient Blood Management Program; by Pfizer for investigator-initiated trial; honoraria for scientific lectures from B. Braun Melsungen, Vifor Pharma, Ferring, CSL Behring, Heinen&Löwenstein, and Aesculap Academy. H. Neb, L. Judd und G. Hintereder geben an, dass kein Interessenkonflikt besteht.

Dieser Beitrag beinhaltet keine von den Autoren durchgeführten Studien an Menschen oder Tieren.

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Neb, H., Judd, L., Hintereder, G. et al. Laborüberdiagnostik und iatrogene Anämie. Wien klin Mag 21, 194–199 (2018). https://doi.org/10.1007/s00740-018-0237-y

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  • DOI: https://doi.org/10.1007/s00740-018-0237-y

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