Summary.
Chloranil and 2,3-dichloro-1,4-naphthoquinone have been linked to different natural and unnatural amino acids via a vinylic spacer. Two routes were developed for the facile preparation of these novel modified amino acids: the direct method, which can only be applied to secondary amines, and the indirect method (transamination reaction), which can be applied to any amino acid or ester.
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Received June 16, 2000 Accepted August 28, 2000
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Alnabari, M., Bittner, S. New quinone-amino acid conjugates linked via a vinylic spacer. Amino Acids 20, 381–387 (2001). https://doi.org/10.1007/s007260170034
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DOI: https://doi.org/10.1007/s007260170034