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Non-biological selectivity in amino acids polymerization on TiO2 nanoparticles

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Abstract

For the first, time a strong selectivity is evidenced in inorganic peptide synthesis. When an equimolar mixture of Ala and Arg monomers is added to the synthesis medium of TiO2 nanoparticles from Ti(IV) isopropoxide in benzyl alcohol, the Ala-Arg dipeptide is observed by 13C NMR in the resulting solid, at the exclusion of other dipeptides or higher peptides.

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Fig. 1
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The authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. Laboratoire de Réactivité de Surface, Case courrier 178, 3 Rue Galilée, 94200, Ivry-sur-Seine, France

    Maguy Jaber, Jolanda Spadavecchia, Houssein Bazzi, Thomas Georgelin, France Costa-Torro & Jean-François Lambert

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  1. Maguy Jaber
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  2. Jolanda Spadavecchia
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  3. Houssein Bazzi
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  4. Thomas Georgelin
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  5. France Costa-Torro
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  6. Jean-François Lambert
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Correspondence to Jean-François Lambert.

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Jaber, M., Spadavecchia, J., Bazzi, H. et al. Non-biological selectivity in amino acids polymerization on TiO2 nanoparticles. Amino Acids 45, 403–406 (2013). https://doi.org/10.1007/s00726-013-1516-y

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  • DOI: https://doi.org/10.1007/s00726-013-1516-y

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