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Polyamines: metabolism to systems biology and beyond

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Summary.

Polyamines and the metabolic and physiopathological processes in which they are involved represent an active field of research that has been continuously growing since the seventies. In the last years, the trends in the focused areas of interest within this field since the 1970s have been confirmed. The impact of “-omics” in polyamine research remains too low in comparison with its deep impact on other biological research areas. These high-throughput approaches, along with systems biology and, in general, more systemic and holistic approaches should contribute to a renewal of this research area in the near future.

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Abbreviations

ADME/Tox:

absorption, distribution, metabolism, excreton and toxicity

HTML:

hypertext markup language

HTTP:

hypertext transfer protocol

SAM:

S-adenosyl methionine

siRNA:

small interferent RNA

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Authors and Affiliations

  1. Procel Group, Department of Molecular Biology and Biochemistry, University of Málaga, and Ciberer, Málaga, Spain

    R. Montañez, F. Sánchez-Jiménez & M. Á. Medina

  2. Khaos Group, Department of Computer Languages and Computing Sciences, University of Málaga, Málaga, Spain

    J. F. Aldana-Montes

Authors
  1. R. Montañez
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  2. F. Sánchez-Jiménez
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  3. J. F. Aldana-Montes
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  4. M. Á. Medina
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Montañez, R., Sánchez-Jiménez, F., Aldana-Montes, J. et al. Polyamines: metabolism to systems biology and beyond. Amino Acids 33, 283–289 (2007). https://doi.org/10.1007/s00726-007-0521-4

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