Skip to main content
SpringerLink
Log in

720 MHz Pulse EPR Imager with Arbitrary Waveform Generator-Based Bridge and Direct Sampling

  • Original Paper
  • Published:
Applied Magnetic Resonance Aims and scope Submit manuscript

Abstract

A pulse 720 MHz EPR imager with a permanent magnet, arbitrary waveform generator based excitation, and detection system operating in the direct sampling and signal down-conversion modes is presented. This flexible instrument allowed testing various acquisition modes and demonstrating its signal to noise ratio advantage over the previously used 250 MHz instrument.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5
Fig. 6

Similar content being viewed by others

References

  1. N. Devasahayam, R. Murugesan, K. Matsumoto, J.B. Mitchell, J.A. Cook, S. Subramanian, M.C. Krishna, J. Magn. Reson. 168, 110–117 (2004)

    Article  ADS  Google Scholar 

  2. M. Tseitlin, R.W. Quine, G.A. Rinard, S.S. Eaton, G.R. Eaton, J. Magn. Reson. 213, 119–125 (2011)

    ADS  Google Scholar 

  3. P.E. Spindler, Y. Zhang, B. Endeward, N. Gershernzon, T.E. Skinner, S.J. Glaser, T.F. Prisner, J. Magn. Reson. 218, 49–58 (2012)

    Article  ADS  Google Scholar 

  4. A. Doll, S. Pribitzer, R. Tschaggelar, G. Jeschke, J. Magn. Reson. 230, 27–39 (2013)

    Article  ADS  Google Scholar 

  5. H. Sato-Akaba, M. Tseytlin, J. Magn. Reson. 304, 42–52 (2019)

    Article  ADS  Google Scholar 

  6. R.H. Pursley, G. Salem, T.J. Pohida, N. Devasahayam, S. Subramanian, M.C. Krishna, Rev. Sci. Instrum. 76(3), 1–6 (2005). https://doi.org/10.1063/1.1903163

    Article  Google Scholar 

  7. S. Subramanian, R. Murugesan, N. Devasahayam, J.A. Cook, M. Afeworki, T. Pohida, R.G. Tschudin, J.B. Mitchell, M.C. Krishna, J. Magn. Reson. 137, 379–388 (1999)

    Article  ADS  Google Scholar 

  8. G. Schwarz, Munchner Medizinische Wochenschrift 56, 1217–1218 (1909)

    Google Scholar 

  9. R.H. Thomlinson, L.H. Gray, Br. J. Radiol. 9, 539–563 (1955)

    Google Scholar 

  10. R. Turner, Magn. Reson. Imaging 11, 903–920 (1993)

    Article  Google Scholar 

  11. S.V. Sundramoorthy, B. Epel, H.J. Halpern, Appl. Magn. Reson. 48, 805–811 (2017)

    Article  Google Scholar 

  12. B. Epel, M.K. Bowman, C. Mailer, H.J. Halpern, Magnet Reson Med 72, 362–368 (2014)

    Article  Google Scholar 

  13. B. Epel, S.V. Sundramoorthy, C. Mailer, H.J. Halpern, Conc. Magn. Reson. B 33B, 163–176 (2008)

    Article  Google Scholar 

  14. K.J. Liu, P. Gast, M. Moussavi, S.W. Norby, N. Vahidi, T. Walczak, M. Wu, H.M. Swartz, Proc. Natl Acad. Sci. USA 90, 5438–5442 (1993)

    Article  ADS  Google Scholar 

  15. G.A. Rinard, R.W. Quine, J.R. Harbridge, R.T. Song, G.R. Eaton, S.S. Eaton, J. Magn. Reson. 140, 218–227 (1999)

    Article  ADS  Google Scholar 

  16. B. Epel, H.J. Halpern, Emagres 6, 149–160 (2017)

    Article  ADS  Google Scholar 

  17. H.J. Halpern, M.K. Bowman, EPR Imaging at MHz frequencies, in EPR Imaging and in vivo EPR. ed. by G.R. Eaton, S.S. Eaton, eK. Ohno (CRC Press, Boca Raton, FL, 1991)

    Google Scholar 

  18. G.A. Rinard, S.S. Eaton, G.R. Eaton, J.C.P. Poole, H.A. Farach, in Handbook of electron spin resonance. ed. by C. Poole, H. Farach (New York, Springer Verlag, 1999)

    Google Scholar 

  19. G.A. Rinard, R.W. Quine, S.S. Eaton, G.R. Eaton, J Magn Reson 156, 113–121 (2002)

    Article  ADS  Google Scholar 

  20. R.T. Weber, J.A.J.M. Disselhorst, L.J. Prevo, J. Schmidt, W.T. Wenckebach, J. Magn. Reson. 81, 129–144 (1989)

    ADS  Google Scholar 

  21. R. Nakaoka, D. Komarov, S. Matsumoto, H. Hirata, Appl. Magn. Reson. 49, 853–867 (2018)

    Article  Google Scholar 

  22. G.A. Rinard, R.W. Quine, L.A. Buchanan, S.S. Eaton, G.R. Eaton, B. Epel, S.V. Sundramoorthy, H.J. Halpern, Appl. Magn. Reson. 48, 1227–1247 (2017)

    Article  Google Scholar 

  23. M. Tseytlin, B. Epel, S. Sundramoorthy, D. Tipikin, H.J. Halpern, J. Magn. Reson. 272, 91–99 (2016)

    Article  ADS  Google Scholar 

  24. B. Epel, M.K. Bowman, C. Mailer, H.J. Halpern, Magn Reson Med 72, 362–368 (2014)

    Article  Google Scholar 

Download references

Acknowledgements

We acknowledge our colleagues from the Center for EPR Imaging In vivo Physiology at the University of Chicago and National Institutes of Health (NIH USA) grants P41EB002034, R01CA098575, and R50 CA211408. BE and HJH are are also members of a start-up company O2M Technologies.

Author information

Authors and Affiliations

  1. Center for EPR Imaging In Vivo Physiology, Department of Radiation and Cellular Oncology, University of Chicago, Chicago, IL, USA

    Boris Epel, Subramanian V. Sundramoorthy & Howard J. Halpern

Authors
  1. Boris Epel
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Subramanian V. Sundramoorthy
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Howard J. Halpern
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Boris Epel.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Epel, B., Sundramoorthy, S.V. & Halpern, H.J. 720 MHz Pulse EPR Imager with Arbitrary Waveform Generator-Based Bridge and Direct Sampling. Appl Magn Reson 52, 1031–1040 (2021). https://doi.org/10.1007/s00723-021-01315-4

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00723-021-01315-4

Search

Navigation