Abstract
Magnetic resonance imaging (MRI) and magnetic resonance spectroscopy (MRS) are non-invasive techniques for tissue characterization. MRI/MRS in small phantoms with a clinical magnetic resonance scanner requires the design and development of dedicated radiofrequency coils. This paper describes the simulation, design, and application of a 1H transmit/receive Helmholtz coil, suitable for MRI/MRS studies in small phantoms with a clinical 3T scanner. Coil inductance and resistance were analytically calculated by taking into account the conductors cross geometry while magnetic field and sample-induced resistance were calculated with magnetostatic approaches. Finally, the coil sensitivity was measured with the perturbing sphere method. Successively, a coil prototype was built and tested on the workbench and by acquisition of MRI and MRS data. Results show that such coil could provide a low cost and easy to build device for MRI/MRS experiments with a clinical scanner in small specimens.
Similar content being viewed by others
References
M.F. Santarelli, V. Positano, G. Giovannetti, F. Frijia, L. Menichetti, J.H. Ardenkjaer-Larsen, D. De Marchi, V. Lionetti, G. Aquaro, M. Lombardi, L. Landini, NMR in Biomed. 25, 925–934 (2012)
D.I. Hoult, R.E. Richards, J. Magn. Reson. 24, 71–85 (1976)
K. Derby, J. Tropp, C. Hawryszko, J. Magn. Reson. 86, 645–651 (1990)
J. Jin, Electromagnetic Analysis and Design in Magnetic Resonance Imaging (CRC, Boca Raton, 1999)
J. Mispelter, M. Lupu, A. Briguet, NMR Probeheads for Biophysical and Biomedical Experiments (Imperial College Press, London, 2015)
G. Giovannetti, Conc. Magn. Reson. Part B 46B, 146–155 (2016)
S.E. Hurlston, G.P. Cofer, G.A. Johnson, Int. J. Imaging Syst. Technol. 8, 277–284 (1997)
C. Chen, D.J. Hoult, Biomedical Magnetic Resonance Technology (IOP, Bristol, 1989)
M.D. Harpen, Med. Phys. 14(4), 616–618 (1987)
L. Darrasse, G. Kassab, Rev. Sci. Instrum. 64, 1841–1844 (1993)
M. Alecci, I. Seimenis, S.J. McCallum, D.J. Lurie, M.A. Foster, Phys. Med. Biol. 43, 1899–1905 (1998)
G. Giovannetti, F. Frijia, L. Menichetti, J.H. Ardenkjaer-Larsen, V. Hartwig, D. De Marchi, V. Positano, L. Landini, M. Lombardi, M.F. Santarelli, Appl. Magn. Reson. 42, 511–518 (2012)
T. Schirmer, B. Wener, I. Hancu, E. Martin, Proc. Intl. Soc. Mag. Reson. Med. 13, 2504 (2005)
B.S. Li, J. Regal, O. Gonen, Magn. Reson. Med. 46(6), 1049–1053 (2001)
H.C. Taylor, M. Burl, J.W. Hand, Phys. Med. Biol. 42, 1395–1402 (1997)
G. Giovannetti, V. Hartwig, L. Landini, M.F. Santarelli, Appl. Magn. Reson. 39, 391–399 (2010)
G. Giovannetti, G. Tiberi, Appl. Magn. Reson. 47, 601–612 (2016)
G. Giovannetti, V. Hartwig, L. Landini, M.F. Santarelli, Appl. Magn. Reson. 40, 351–361 (2011)
N.R. Jagannathan, M. Kumar, V. Seenu, O. Coshic, S.N. Dwivedi, P.K. Julka, A. Srivastava, G.K. Rath, Br. J. Cancer 84(8), 1016–1022 (2001)
M. Castillo, J.K. Smith, L. Kwock, Am. J. Neuroradiol. 21(9), 1645–1649 (2000)
Author information
Authors and Affiliations
Corresponding author
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
About this article
Cite this article
Giovannetti, G., Frijia, F., Flori, A. et al. Design and Simulation of a Helmholtz Coil for Magnetic Resonance Imaging and Spectroscopy Experiments with a 3T MR Clinical Scanner. Appl Magn Reson 50, 1083–1097 (2019). https://doi.org/10.1007/s00723-019-01141-9
Received:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s00723-019-01141-9