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Applied Magnetic Resonance

, Volume 49, Issue 4, pp 389–401 | Cite as

31P NMR Manifestation of Metabolic Changes in Blood of Spinal Cord Injured Rats

  • S. V. Yurtaeva
  • M. Yu. Volkov
  • G. G. Yafarova
  • D. I. Silantyeva
  • E. I. Yamalitdinova
Original Paper
  • 154 Downloads

Abstract

The 31P nuclear magnetic resonance spectroscopy technique was applied to study the blood of rats with a 3-day spinal cord injury and control rats. Phosphorus-containing blood metabolites: 2,3-diphosphoglycerates, inorganic phosphates, phospholipids, ATP and adenosine monophosphates were detected and quantitatively evaluated. It was found that the amount of 2,3-diphosphoglycerates, inorganic phosphates, phospholipids and adenosine monophosphates increase, and pH of the blood decreases after spinal cord injury. The results demonstrate increased hypoxia in injured rats.

Notes

Acknowledgements

The reported study was supported by Scientific Program of the Presidium of the Russian Academy of Sciences no. 5 and it was also funded by the Russian Foundation for Basic Research (project no. 17-04-01746 A).

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Copyright information

© Springer-Verlag GmbH Austria, part of Springer Nature 2018

Authors and Affiliations

  • S. V. Yurtaeva
    • 1
  • M. Yu. Volkov
    • 1
  • G. G. Yafarova
    • 1
    • 2
  • D. I. Silantyeva
    • 2
  • E. I. Yamalitdinova
    • 2
  1. 1.Kazan Physical-Technical Institute, KSC, RASKazanRussia
  2. 2.Institute of Fundamental Medicine and BiologyKazan Federal UniversityKazanRussia

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