Porcine-like G3P and G4P rotavirus A strains detected from children with diarrhoea in Vietnam
Animal rotavirus A (RVA) strains can infect children and cause diarrhoea. We determined the full genome sequences of one G3P strain (NT0001) and five G4P strains (NT0042, NT0077, NT0205, NT0599, and NT0621) detected from children with diarrhoea in Vietnam in 2007-2008. Strain NT0001 had a genotype constellation of: G3-P-I5-R1-C1-M1-A8-N1-T1-E1-H1, strain NT0042: G4-P-I1-R1-C1-M1-A8-N1-T1-E1-H1, strain NT0077: G4-P-I5-R1-C1-M1-A8-N1-T7-E1-H1, and strains NT0205, NT0599, and NT0621: G4-P-I1-R1-C1-M1-A1-N1-T1-E1-H1. Sequence divergence data and phylogenetic analysis showed that they were different porcine RVA strains that independently and directly crossed the host species barrier to infect children.
Japan Agency for Medical Research and Development (AMED: 15fm0108001h001).
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Conflict of interest
None to declare.
Approved by the review boards of relevant institutions.
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