Detection in Japan of an equine-like G3P reassortant rotavirus A strain that is highly homologous to European strains across all genome segments
Equine-like G3P rotavirus A strains with DS-1-like backbone genes have emerged since 2013. An equine-like RVA/Human-wt/JPN/15R429/2015/G3P strain possessing I2-R2-C2-M2-A2-N2-T2-E2-H2 was detected in Japan in 2015. Its VP7 gene was ≥ 99.3% identical to those of equine-like G3P strains detected in Japan, and the remaining 10 genes were 98.6-99.8% identical to G1P double-gene reassortants detected in Japan, Thailand and the Philippines. Thus, 15R429 was likely generated through reassortment between the equine-like G3P and G1P reassortant strains. Notably, 15R429 was 98.5-99.8% identical across all 11 genes of the equine-like G3P strains detected in Spain and Hungary in 2015.
The authors thank S. Miura and the staff of Yuri-Kumiai General Hospital for sample collection, and Y. Baba and H. Sugawara for their technical assistance.
Compliance with ethical standards
Japan Agency for Medical Research and Development, and the intramural fund of the Department of Paediatrics, Akita University Graduate School of Medicine.
Conflict of interest
None to declare.
Approved by the review boards of all relevant institutions.
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