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The long-term effects of microvascular decompression on social phobia and health-related quality of life in patients with hemifacial spasm: a 3-year prospective study

  • Original Article - Functional Neurosurgery - Other
  • Published:
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Abstract

Background

Although not a life-threatening condition, hemifacial spasm (HFS) frequently leads to social phobia because it causes significant facial disfigurement and consequently reduces health-related quality of life (HRQoL). The purpose of the current study was to examine the long-term effects of MVD on psychological aspects and HRQoL in HFS patients with social anxiety over a 36-month follow-up.

Methods

Thirty patients with HFS who underwent MVD from January 2015 to May 2015 were included in this prospective study. Clinical data, including standardized measures of general anxiety and depression (Hospital Anxiety Depression Scale (HADS)), social anxiety (Liebowitz Social Anxiety Scale (LSAS)), and the severity of HFS, were collected postoperatively, and 6 months and 36 months after MVD. Likewise, data on HRQoL were collected at baseline, and 6 months and 36 months after MVD using the Korean version of the Short Form 36 (SF-36).

Results

Twenty-two patients who completed the 36-month follow-up were classified into social phobia group and non-social phobia group based on the LSAS total scores of 60. Repeated measures analysis of variance demonstrated significant differences between the two groups over time for the total LSAS score (p < 0.001), anxiety subscale score of the HADS (p = 0.002), and the Mental Component Summary (MCS) (p = 0.046) of the SF-36. A comparison of these two groups in terms of differences observed in their scales at 6 months after MVD has shown that the improvements of the social phobia group in HADS anxiety subscale (p = 0.010), LSAS total score (p = 0.008), and MCS (p = 0.040) were significantly more improved than the those of non-social phobia group. And at 36 months after surgery, the improvement of the scales mentioned above was maintained, and additionally Vitality (p = 0.040) and Mental Health (p = 0.040) dimensions showed a statistically significant improvement.

Conclusions

The improvements previously observed in psychological aspects and HRQoL over a short-term follow-up after MVD in HFS patients with social phobia were maintained for at least 36 months after MVD.

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Abbreviations

HFS:

Hemifacial spasm

MVD:

Microvascular decompression

HRQoL:

Health-related quality of life

LSAS:

Leibowitz Social Anxiety Scale

HADS:

Hospital Anxiety Depression Scale

SF-36:

Short Form 36

PF:

Physical Functioning

RP:

Role-Physical

BP:

Bodily Pain

GH:

General Health

VT:

Vitality

SF:

Social Functioning

RE:

Role-Emotional

MH:

Mental Health

PCS:

Physical Component Summary

MCS:

Mental Component Summary

RMANOVA:

Repeated measures analysis of variance

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Authors and Affiliations

  1. Department of Neurosurgery, Ewha Womans University Mokdong Hospital, Ewha Womans University College of Medicine, Seoul, Republic of Korea

    Young Goo Kim

  2. Department of Neurosurgery, Brain Research Institute, Yonsei University College of Medicine, Seoul, Republic of Korea

    Won Seok Chang, Hyun Ho Jung & Jin Woo Chang

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  1. Young Goo Kim
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  2. Won Seok Chang
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  4. Jin Woo Chang
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Correspondence to Jin Woo Chang.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Kim, Y.G., Chang, W.S., Jung, H.H. et al. The long-term effects of microvascular decompression on social phobia and health-related quality of life in patients with hemifacial spasm: a 3-year prospective study. Acta Neurochir 161, 2035–2042 (2019). https://doi.org/10.1007/s00701-019-04023-y

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  • DOI: https://doi.org/10.1007/s00701-019-04023-y

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