Response to the Letter to the Editor “Lipomatosis of nerve and overgrowth syndrome: an intriguing and still unclear correlation”
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To the editor,
We appreciate the letter to the editor by Vetrano et al.  regarding our recent paper on lipomatosis of nerve (LN) . Our group has been interested in LN as well as other adipose lesions of nerves for many years [3, 4, 9].
First, we agree with the authors that there is a great inconsistency in the terminology in the world’s literature of LN. Besides the term lipomatosis of nerve, which has been proposed by WHO in 2002 , many other terms are regularly used including fibrolipomatous hamartoma, lipofibromatous hamartoma, neural lipoma, and macrodystrophia lipomatosa, for a spectrum of pathologies. This terminology problem was one of the major reasons that we decided to compile the world’s literature and perform the systematic review (which included the recent case by Vetrano et al. ). Our systematic review is now published in JNS . This study strengthened the association of LN and nerve-territory overgrowth. We then utilized the raw data from this large...
- 2.Fletcher C, Unni K, Mertens F (2002) World Health Organisation classification of tumours. In: Pathology and genetics: tumours of soft tissue and bone. IARC Press, LyonGoogle Scholar
- 6.Marek T, Spinner RJ, Syal A, Mahan MA (2019) Strengthening the association of lipomatosis of nerve and nerve-territory overgrowth: a systematic review. J Neurosurg. https://doi.org/10.3171/2018.12.JNS183050
- 10.Vetrano IG, Sconfienza LM, Albano D, Chianca V, Nazzi V (2018) Recurrence of carpal tunnel syndrome in isolated non-syndromic macrodactyly: DTI examination of a giant median nerve. Skelet Radiol. https://doi.org/10.1007/s00256-018-3098-y
- 11.Vetrano IG, Sconfienza LM, Devigili G, Nazzi V (2019) Lipomatosis of nerve and overgrowth syndrome: an intriguing and still unclear correlation. Acta Neurochir (in press)Google Scholar