Lipomatosis of nerve and overgrowth syndrome: an intriguing and still unclear correlation
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We read with great interest the paper by Marek and co-authors entitled “Lipomatosis of nerve and overgrowth: is there a preference for motor (mixed) vs. sensory nerve involvement?” which recently appeared as “Online First Articles” in Acta Neurochirurgica .
Based on their extensive experience in this field [2, 3, 7], the authors present a summary literature review along with their Institutional cases of nerve lipomatosis (LN). This intriguing and in many ways still unclear condition consists of a fibroadipose epineurial proliferation, frequently associated with bone and soft-tissue enlargement. Due to the epineural and perineural fibrosis, nerve bundles can be strongly compressed, leading to an entrapment neuropathy . Gigantism and overgrowth as asymmetric macrodactyly generally interest a part or a whole extremity, usually corresponding to the territory of distribution of a single nerve. Marek and coworkers analyzed the prevalence of overgrowth syndrome and nerves...
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The authors declare that they have no conflict of interest.
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