Acta Neurochirurgica

, Volume 161, Issue 6, pp 1191–1195 | Cite as

Internal carotid artery aneurysms diagnosed after stereotactic radiosurgery for a growth hormone-secreting pituitary adenoma: a case report and literature review

  • Hirotaka Inoue
  • Takayuki KawanoEmail author
  • Yuki Ohmori
  • Toshihiro Amadatsu
  • Haruaki Yamamoto
  • Toru Nishi
  • Akitake Mukasa
Case Report - Vascular Neurosurgery - Aneurysm
Part of the following topical collections:
  1. Vascular Neurosurgery – Aneurysm


Radiation therapy is associated with the subsequent development of cerebral aneurysms; however, stereotactic radiosurgery (SRS)-associated aneurysm cases have not been well documented, with only 18 cases reported to date. We present a case of intracranial aneurysms with the rupture occurring 20 years after SRS for a growth hormone-producing pituitary adenoma. This is the first report of aneurysms diagnosed following transsphenoidal surgery and SRS for pituitary adenoma. We believe that the aneurysm reported here is a consequence of the SRS treatment, and thus this may be a very rare long-term complication following radiation treatments.


Aneurysm Stereotactic radiosurgery Gamma knife Pituitary adenoma 



Arteriovenous malformation


External carotid artery


Growth hormone-producing pituitary adenoma


Gamma knife surgery


Internal carotid artery


Middle cerebral artery


Magnetic resonance imaging


Stereotactic radiosurgery


Superficial temporal artery


Transsphenoidal surgery


Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflicts of interest.

Informed consent

The patient has consented to the submission of this case report to the journal.

Supplementary material

701_2019_3840_MOESM1_ESM.docx (43 kb)
ESM 1 (DOCX 43 kb)


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Copyright information

© Springer-Verlag GmbH Austria, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Departments of Neurosurgery, Graduate School of Medical SciencesKumamoto UniversityKumamotoJapan
  2. 2.Department of NeurosurgerySaiseikai Kumamoto HospitalKumamotoJapan

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