Acta Neurochirurgica

, Volume 160, Issue 12, pp 2307–2312 | Cite as

The implementation of an infection prevention bundle reduces surgical site infections following cranial surgery

  • Ann-Kathrin JörgerEmail author
  • Nikolaus Wimmer
  • Nicole Lange
  • Arthur Wagner
  • Insa Janssen
  • Sandro Krieg
  • Bernhard Meyer
  • Ehab Shiban
Original Article - Infection
Part of the following topical collections:
  1. Infection



The benefit of an infection prevention bundle made up of five basic procedures to avoid surgical site infections (SSIs) following cranial surgery was evaluated.


Data from all patients with first time elective brain surgery from March 2014 till May 2016 were analyzed. In April 2015, an infection prevention bundle was implemented. The rate of SSIs after first time elective cranial surgery of patients operated 1 year before and 1 year after the implementation was compared.


Of the 321 cases operated before the implementation of the infection prevention bundle, 13 cases (4%) developed a SSI. After the implementation, only 6 patients out of 288 were re-operated due to a SSI (2%). The most frequent etiological germ cultivated was Staphylococcus aureus.


The implementation of a bundle of 5 basic infection prevention steps leads to a clinical relevant reduction of SSIs.


Surgical site infection SSI Infection prevention bundle Cranial surgery 



Surgical site infection


Cerebrospinal fluid


American Society of Anesthesiologists


Compliance with ethical standards

Conflict of interest

Sandro Krieg (SK) is consultants for Nexstim Plc (Helsinki, Finland) and received honoraria from Medtronic (Meerbusch, Germany) and Carl Zeiss Meditec (Oberkochen, Germany). SK and Bernhard Meyer (BM) received research grants and are consultants for Brainlab AG (Munich, Germany). BM received honoraria, consulting fees, and research grants from Medtronic (Meerbusch, Germany), icotec ag (Altstätten, Switzerland), and Relievant Medsystemy Inc. (Sunnyvale, CA, USA), honoraria, and research grants from Ulrich Medical (Ulm, Germany), honoraria and consulting fees from Spineart Deutschland GmbH (Frankfurt, Germany) and DePuy Synthes (West Chester, PA, USA), and royalties from Spineart Deutschland GmbH (Frankfurt, Germany).

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the ethical committee of the faculty of medicine of Technische Universität München and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. For this type of study, formal consent is not required.


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Copyright information

© Springer-Verlag GmbH Austria, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of NeurosurgeryKlinikum rechts der Isar, Technical University of MunichMunichGermany
  2. 2.Department of NeurosurgeryKlinikum rechts der IsarMunichGermany

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