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Tumor-to-tumor metastasis of lung adenocarcinoma into a spinal intradural solitary fibrous tumor: a case report

  • Case Report - Tumor-Other
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Abstract

Solitary fibrous tumors (SFTs) are rare mesenchymal neoplasms commonly involving visceral or parietal pleura. We present the first report of tumor-to-tumor metastasis involving a pulmonary adenocarcinoma donor and an intradural SFT recipient. The patient presented with a 1 year history of diffuse back pain. A spinal intradural contrast-enhancing mass at the T9/10 level and a tumor of the lung were diagnosed radiologically. Bronchoscopic biopsy confirmed pulmonary adenocarcinoma in the right upper lung lobe. Due to deteriorating neurological status with conus medullaris syndrome, we performed a neurosurgical excision of the lesion. Histological analysis of the tumor revealed tumor-to-tumor metastasis of the adenocarcinoma to the SFT.

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Abbreviations

CD34:

Cluster of differentiation 34

CT:

Computed tomography

EMA:

Epithelial membrane antigen

MRI:

Multiple resonance imaging

SFT:

Solitary fibrous tumors

STAT6:

Signal transducer and activator of transcription 6

TTF-1:

Thyroid transcription factor-1

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Acknowledgements

The authors would like to thank EDITAGE (www.editage.com) for editing the manuscript.

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Authors and Affiliations

  1. Department of Neurosurgery, Winterthur Cantonal Hospital, Brauerstrasse 15, 8401, Winterthur, Switzerland

    Lazar Tosic, Dominik Baschera, Thomas Feuerstein & Alex Alfieri

  2. Department of Pathology, Winterthur Cantonal Hospital, Brauerstrasse 15, 8401, Winterthur, Switzerland

    Bastian Jentsch

  3. Brandenburg Medical School, Fehrbellinerstrasse 38, 16816, Neuruppin, Germany

    Alex Alfieri

Authors
  1. Lazar Tosic
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  2. Dominik Baschera
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  3. Bastian Jentsch
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  4. Thomas Feuerstein
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  5. Alex Alfieri
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Corresponding author

Correspondence to Lazar Tosic.

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The authors declare that they have no conflict of interest.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from the participant included in the study.

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This article is part of the Topical Collection on Tumor-Other

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Tosic, L., Baschera, D., Jentsch, B. et al. Tumor-to-tumor metastasis of lung adenocarcinoma into a spinal intradural solitary fibrous tumor: a case report. Acta Neurochir 160, 2393–2396 (2018). https://doi.org/10.1007/s00701-018-3700-z

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  • DOI: https://doi.org/10.1007/s00701-018-3700-z

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