Acta Neurochirurgica

, Volume 160, Issue 5, pp 1029–1039 | Cite as

Post-operative imaging assessment of non-functioning pituitary adenomas

  • Kunal S. Patel
  • Sanjay Dhawan
  • Renzhi Wang
  • Bob S. Carter
  • James Y. Chen
  • Clark C. Chen
Review Article - Pituitaries
  • 57 Downloads

Abstract

Background

Non-functioning pituitary adenomas (NFAs) are the most common pituitary tumors. There is significant variability in clinical practice in terms of post-operative imaging evaluation. The objective of this manuscript is to provide an exhaustive review of published articles pertaining to the post-operative imaging evaluation of NFAs.

Methods

The MEDLINE database was queried for studies investigating imaging for the post-operative evaluation of pituitary adenomas. From an initial search of 5589 articles, 37 articles were evaluated in detail and included in this review.

Results

Magnetic resonance imaging (MRI) is the gold standard for post-operative monitoring of NFAs, although functional imaging modalities may improve identification of residual tumor in conjunction with MRI. The residual tumor can be distinguished from post-operative changes by experienced practitioners using high-resolution MRI in the immediate post-operative setting (within 1 week of surgery). However, continued imaging evolution in the appearance of residual tumor or resection cavity is expected up to 3 months post-operatively.

Conclusions

Post-operative imaging appearance of the pituitary gland, optic apparatus, and pneumocephalus patterns, correlated with the clinical outcomes. Long-term, lifetime follow-up is warranted for NFA patients who underwent surgical resection.

Keywords

Non-functioning pituitary adenomas Post-operative Computed tomography Magnetic resonance imaging 

Notes

Compliance with ethical standards

Informed consent

This manuscript is a review article. For this type of study formal consent is not required.

Conflict of interest

None.

Ethical approval

This manuscript is a review article. For this type of study formal consent is not required.

Animal experiments

This article does not contain any studies with animals performed by any of the authors.

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Copyright information

© Springer-Verlag GmbH Austria, part of Springer Nature 2018

Authors and Affiliations

  • Kunal S. Patel
    • 1
  • Sanjay Dhawan
    • 2
  • Renzhi Wang
    • 3
  • Bob S. Carter
    • 4
  • James Y. Chen
    • 5
    • 6
  • Clark C. Chen
    • 2
  1. 1.Department of NeurosurgeryUniversity of California, Los AngelesLos AngelesUSA
  2. 2.Department of NeurosurgeryUniversity of MinnesotaMinneapolisUSA
  3. 3.Department of NeurosurgeryPeking Union Medical College HospitalBeijingChina
  4. 4.Department of Neurosurgery, Massachusetts General HospitalHarvard Medical SchoolBostonUSA
  5. 5.Department of Radiology, UC San Diego Health SystemUniversity of California, San DiegoLa JollaUSA
  6. 6.Department of RadiologySan Diego Veterans Administration Health SystemSan DiegoUSA

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