Acta Neurochirurgica

, Volume 160, Issue 5, pp 921–922 | Cite as

Response: microdialysis as a useful tool to detect cerebral metabolic crises

  • F. A. Zeiler
  • D. K. Menon
Letter to the Editor (by Invitation) - Brain trauma


  1. 1.
    Zeiler FA, Donnelly J, Smieleweski P, Menon D, Hutchinson PJ, Czosnyka M (2017) Critical thresholds of ICP derived continuous cerebrovascular reactivity indices for outcome prediction in non-craniectomized TBI patients: PRx, PAx and RAC. Dec 14.
  2. 2.
    Zeiler FA, Thelin EP, Helmy A, Czosnyka M, Hutchinson PJA, Menon DK (2017) A systematic review of cerebral microdialysis and outcomes in TBI: relationships to patient functional outcome, neurophysiologic measures, and tissue outcome. Acta Neurochir 159(12):2245–2273CrossRefPubMedPubMedCentralGoogle Scholar
  3. 3.
    Ho CL, Wang CM, Lee KK, Ng I, Ang BT (2008) Cerebral oxygenation, vascular reactivity, and neurochemistry following decompressive craniectomy for severe traumatic brain injury. J Neurosurg 108:943–949CrossRefPubMedGoogle Scholar
  4. 4.
    Bor-Seng-Shu E, Oliveira ML, Teixeira MJ (2010) Traumatic brain injury and metabolism. J Neurosurg 112:1351–1353CrossRefPubMedGoogle Scholar
  5. 5.
    Timofeev I, Czosnyka M, Nortje J, Smielewski P, Kirkpatrick P, Gupta A, Hutchinson PJ (2008) Effect of decompressive craniectomy on intracranial pressure and cerebrospinal compensation following traumatic brain injury. J Neurosurg 108:66–73CrossRefPubMedGoogle Scholar
  6. 6.
    Sorrentino E, Diedler J, Kasprowicz M, Budohoski KP, Haubrich C, Smielewski P, Outtrim JG, Manktelow A, Hutchinson PJ, Pickard JD, Menon DK, Czosnyka M (2012) Critical thresholds for cerebrovascular reactivity after traumatic brain injury. Neurocrit Care 16(2):258–266CrossRefPubMedGoogle Scholar

Copyright information

© Springer-Verlag GmbH Austria, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Division of Anaesthesia, Addenbrooke’s HospitalUniversity of CambridgeCambridgeUK
  2. 2.Department of Surgery, Rady Faculty of Health SciencesUniversity of ManitobaWinnipegCanada
  3. 3.Clinician Investigator Program, Rady Faculty of Health ScienceUniversity of ManitobaWinnipegCanada

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