Ionic covalent organic frameworks for the magnetic solid-phase extraction of perfluorinated compounds in environmental water samples


A novel magnetic ionic covalent organic framework (Fe3O4@EB-iCOFs) was designed and synthesized. It was then characterized by X-ray diffraction, N2 adsorption–desorption analysis, and magnetic measurements, among others. The material shows the advantages of ionic property, large surface area, and magnetic responsiveness. It has potential of magnetic solid-phase extraction (MSPE) of perfluorinated compounds (PFCs). A method for the determination of PFCs based on MSPE-HPLC-MS/MS was established. The method has excellent linearity (r ≥ 0.995) in the working range 1-1000 ng L-1 , good repeatability (1.4–5.8%, n = 6), low limits of detection in the range 0.1–0.8 ng L−1 and satisfactory recoveries (between 73.9 and 108.3%).

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This work was supported by the National Nature Science Foundation of China (Nos. 21777089, 22076086), Key Research and Development Program of Shandong Province (2019GSF111016), Jinan University and Institute Innovation Team Project (2019GXRC032), and Shandong Province Taishan Scholar Program (ts201712063 and ts20190948).

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Correspondence to Xia Wang.

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Jiang, HL., Xue, F., Sun, J. et al. Ionic covalent organic frameworks for the magnetic solid-phase extraction of perfluorinated compounds in environmental water samples. Microchim Acta 188, 47 (2021).

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  • Ionic organic framework 
  • Sample pretreatment
  • Solid-phase extraction
  • Environmental analysis
  • Perfluorinated pollutants