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Amperometric determination of ascorbic acid with a glassy carbon electrode modified with TiO2-gold nanoparticles integrated into carbon nanotubes

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Abstract

A glassy carbon electrode was modified with a TiO2-gold nanoparticle hybrid integrated with multi-walled carbon nanotubes in a dihexadecylphosphate film (TiO2-Au NP-MWCNT-DHP/GCE) and applied to amperometric determination of ascorbic acid (AA). The modified sensor displays fast charge transfer and shows an irreversible anodic behavior for AA by cyclic voltammetry. Under optimal experimental conditions and using amperometry at 0.4 V, the analytical curve presented a statistical linear concentration range for AA from 5.0 to 51 μmol L−1, with a limit of detection of 1.2 μmol L−1. The electrode was successfully applied to the determination of AA in pharmaceutical and fruit juice without the need for major pretreatment of samples.

Schematic of a new sensing platform for ascorbic acid (AA). It is based on a glassy carbon electrode (GCE) modified with TiO2-Au nanoparticles integrated into carbon nanotubes in a dihexadecylphosphate film. The sensor was applied to amperometric determination of AA in juice and pharmaceutical samples.

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Acknowledgements

The authors gratefully acknowledge financial support and scholarships from the funding agencies Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES), Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP; Grant numbers 2015/21366-9 and 2015/11452-5) and Fundação Araucária do Paraná. Special thanks to Juliane Cristina Leme for her kind help in statistical analyses.

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Authors and Affiliations

  1. Departamento de Química, Centro de Ciências Exatas, Universidade Estadual de Londrina (UEL), Rodovia Celso Garcia Cid, PR 445 Km 380, PR, C.P. 10.011, Londrina, 86057-970, Brazil

    Jessica Scremin, Carlos Alberto Rossi Salamanca-Neto & Elen Romão Sartori

  2. Departamento de Química Fundamental, Instituto de Química, Universidade de São Paulo, Av. Prof. Lineu Prestes, 748, São Paulo, SP, 05508-000, Brazil

    Eduardo César Melo Barbosa & Pedro Henrique Cury Camargo

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  1. Jessica Scremin
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  2. Eduardo César Melo Barbosa
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Correspondence to Elen Romão Sartori.

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Scremin, J., Barbosa, E.C.M., Salamanca-Neto, C.A.R. et al. Amperometric determination of ascorbic acid with a glassy carbon electrode modified with TiO2-gold nanoparticles integrated into carbon nanotubes. Microchim Acta 185, 251 (2018). https://doi.org/10.1007/s00604-018-2785-7

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