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Microchimica Acta

, 185:219 | Cite as

Voltammetric determination of 5-hydroxytryptamine based on the use of platinum nanoparticles coated with molecularly imprinted silica

  • Yiwen Yang
  • Yanbo Zeng
  • Chuangui Tang
  • Xudong Zhu
  • Xing Lu
  • Lingyu Liu
  • Zhidong Chen
  • Lei Li
Original Paper

Abstract

The authors describe an electrochemical sensor for the determination of 5-hydroxytryptamine (5-HT; serotonin). It is based on the use of platinum nanoparticles (PtNPs) coated with molecularly imprinted silica (MIS). The MIS-coated PtNPs were prepared from 5-HT, PtNPs, phenyltrimethoxysilane and tetraethoxysilane that act as template, support, functional monomer and cross-linker, respectively. The MIS-coated PtNPs were characterized by Fourier transfer infrared spectroscopy and transmission electron microscopy. The MIS-coated PtNPs were drop-cast onto a glassy carbon electrode (GCE) to obtain an electrochemical sensor for 5-HT which exhibited fast response and high recognition ability for 5-HT. The imprinting factor of this electrode for 5-HT is 4.12, which is higher than that for its analogs. Under optimized conditions and at a typical working potential of 0.29 V (vs. Hg/Hg2Cl2), the electrode has a linear response in the 0.05–80 μM 5-HT concentration range and a 0.02 μM detection limit. The electrode was successfully applied to the determination of 5-HT in human serum samples.

Graphical Abstract

Molecularly imprinted silica-coated platinum nanoparticles were prepared using surface imprinting technique. A glassy carbon electrode modified with the surface imprinted material exhibits fast response in detecting 5-hydroxytryptamine, a low detection limit, good selectivity, reproducibility and stability.

Keywords

Platinum nanoparticles Silica; surface molecular imprinting Molecularly imprinted polymer Sol-gel 5-Hydroxytryptamine Serotonin Electrochemical assay 

Notes

Acknowledgments

This work was supported by the National Natural Science Foundation of China (No. 21507041, 21677060), the Zhejiang Provincial Natural Science Foundation of China under Grant No. LY16B050007 and LQ14B050002, the Program for Public technology of Zhejiang Province (No. LGF18B050004), and the Program for Science and Technology of Jiaxing (2017AY33034).

Compliance with ethical standards

The author(s) declare that they have no competing interests.

Supplementary material

604_2018_2755_MOESM1_ESM.doc (5.9 mb)
ESM 1 (DOC 6024 kb)

References

  1. 1.
    Ressler KJ, Nemeroff CB (2000) Role of serotonergic and noradrenergic systems in the pathophysiology of depression and anxiety disorders. Depress Anxiety 12:2–19CrossRefGoogle Scholar
  2. 2.
    Xue C, Wang X, Zhu WY, Han Q, Zhu CH, Hong JL, Zhou XM, Jiang HJ (2014) Electrochemical serotonin sensing interface based on double-layered membrane of reduced graphene oxide/polyaniline nanocomposites and molecularly imprinted polymers embedded with gold nanoparticles. Sensors Actuators B Chem 196:57–63CrossRefGoogle Scholar
  3. 3.
    Shi HM, Wang B, Niu LM, Cao MS, Kang WJ, Lian KQ, Zhang PP (2017) Trace level determination of 5-hydroxytryptamine and its related indoles in amniotic fluid by gas chromatography-mass spectrometry. J Pharm Biomed Anal 143:176–182CrossRefGoogle Scholar
  4. 4.
    Wu D, Xie H, Lu HF, Li W, Zhang QL (2016) Sensitive determination of norepinephrine, epinephrine, dopamine and 5-hydroxytryptamine by coupling HPLC with [Ag(HIO6)2]5−-luminol chemiluminescence detection. Biomed Chromatogr 30:1458–1466CrossRefGoogle Scholar
  5. 5.
    Israël M (2003) A chemiluminescent serotonin assay. Neurochem Int 42:215–220CrossRefGoogle Scholar
  6. 6.
    Zhang LL, Zhao YS, Huang JM, Zhao SL (2014) Simultaneous quantification of 5-hydroxyindoleacetic acid and 5-hydroxytryptamine by capillary electrophoresis with quantum dot and horseradish peroxidase enhanced chemiluminescence detection. J Chromatogr B 967:190–194CrossRefGoogle Scholar
  7. 7.
    Zhang LM, Wang JL, Tian Y (2014) Electrochemical in-vivo sensors using nanomaterials made from carbon species, noble metals, or semiconductors. Microchim Acta 181:1471–1484CrossRefGoogle Scholar
  8. 8.
    Taleat Z, Khoshroo A, Mazloum-Ardakani M (2014) Screen-printed electrodes for biosensing: a review (2008–2013). Microchim Acta 181:865–891CrossRefGoogle Scholar
  9. 9.
    Sanghavi BJ, Wolfbeis OS, Hirsch T, Swami NS (2015) Nanomaterial-based electrochemical sensing of neurological drugs and neurotransmitters. Microchim Acta 182:1–41CrossRefGoogle Scholar
  10. 10.
    Zhang CC, Tang J, Huang LL, Li YP, Tang DP (2017) In-situ amplified voltammetric immunoassay for ochratoxin A by coupling a platinum nanocatalyst based enhancement to a redox cycling process promoted by an enzyme mimic. Microchim Acta 184:2445–2453CrossRefGoogle Scholar
  11. 11.
    Uson L, Hueso JL, Sebastian V, Arenal R, Florea I, Irusta S, Arruebo M, Santamaria J (2017) In-situ preparation of ultra-small Pt nanoparticles within rod-shaped mesoporous silica particles: 3-D tomography and catalytic oxidation of n-hexane. Catal Commun 100:93–97CrossRefGoogle Scholar
  12. 12.
    Yano K, Zhang SY, Pan XQ, Tatsuda N (2014) Investigation of the stability of Platinum nanoparticles incorporated in mesoporous silica with different pore sizes. J Colloid Interface Sci 421:22–26CrossRefGoogle Scholar
  13. 13.
    Oh J, Kim H (2013) Synthesis of core–shell nanoparticles with a Pt nanoparticle core and a silica shell. Curr Appl Phys 13(1):130–136CrossRefGoogle Scholar
  14. 14.
    Prashar AK, Mayadevi S, Rajamohanan P, Devi RN (2011) In situ encapsulation of Pt nanoparticles in mesoporous silica: Synthesis, characterisation and effect of particle size on CO oxidation. App Catal A 403:91–97CrossRefGoogle Scholar
  15. 15.
    Bornacelli J, Silva-Pereyra H, Rodríguez-Fernández L, Avalos-Borja M, Oliver A (2016) From photoluminescence emissions to plasmonic properties in platinum nanoparticles embedded in silica by ion implantation. J Lumin 179:8–15CrossRefGoogle Scholar
  16. 16.
    Tang H, Chen JR, Zeng YB, Li ZY, Huang H, Li L (2016) An electrochemical sensor for 1-naphthylamine based on a novel composite of cyclodextrin-graphene and molecularly imprinted poly(vinylferrocene). Anal Methods 8:1681–1689CrossRefGoogle Scholar
  17. 17.
    Alizadeh T, Hamidi N, Ganjali MR, Rafiei F (2018) Determination of subnanomolar levels of mercury (II) by using a graphite paste electrode modified with MWCNTs and Hg (II)-imprinted polymer nanoparticles. Microchim Acta 185:16CrossRefGoogle Scholar
  18. 18.
    Yu DJ, Zeng YB, Qi YX, Zhou TS, Shi GY (2012) A novel electrochemical sensor for determination of dopamine based on AuNPs@SiO2 core-shell imprinted composite. Biosens Bioelectron 38(1):270–277CrossRefGoogle Scholar
  19. 19.
    Qian K, Deng QL, Fang GZ, Wang JP, Pan MF, Wang S, Pu YH (2016) Metal-organic frameworks supported surface-imprinted nanoparticles for the sensitive detection of metolcarb. Biosens Bioelectron 79:359–363CrossRefGoogle Scholar
  20. 20.
    Wang X, Wang YY, Ye XX, Wu T, Deng HP, Wu P, Li CY (2017) Sensing platform for neuron specific enolase based on molecularly imprinted polymerized ionic liquids in between gold nanoarrays. Biosens Bioelectron 99:34–39CrossRefGoogle Scholar
  21. 21.
    Bali Prasad B, Kumar A, Singh R (2017) Synthesis of novel monomeric graphene quantum dots and corresponding nanocomposite with molecularly imprinted polymer for electrochemical detection of an anticancerous ifosfamide drug. Biosens Bioelectron 94:1–9CrossRefGoogle Scholar
  22. 22.
    Hoa LT, Sun KG, Hur SH (2015) Highly sensitive non-enzymatic glucose sensor based on Pt nanoparticle decorated graphene oxide hydrogel. Sensors Actuators B Chem 210:618–623CrossRefGoogle Scholar
  23. 23.
    Liu M, Zhang J, Yu WW, Liu J (2011) Synthesis of PVP-stabilized Pt/Ru colloidal nanoparticles by ethanol reduction and their catalytic properties for selective hydrogenation of ortho-chloronitrobenzene. J Catal 278:1–7CrossRefGoogle Scholar
  24. 24.
    Patel AN, Unwin PR, Macpherson JV (2013) Investigation of film formation properties during electrochemical oxidation of serotonin (5-HT) at polycrystalline boron doped diamond. Phys Chem Chem Phys 15:18085–18092CrossRefGoogle Scholar
  25. 25.
    Gupta P, Goyal RN (2014) Polymelamine modified edge plane pyrolytic graphite sensor for the electrochemical assay of serotonin. Talanta 120:17–22CrossRefGoogle Scholar
  26. 26.
    Leng Y, Sato K, Li JG, Ishigaki T, Iijima M, Kamiya H, Yoshida T (2009) Iron nanoparticles dispersible in both ethanol and water for direct silica coating. Powder Technol 196:80–84CrossRefGoogle Scholar
  27. 27.
    Tertiș M, Cernat A, Lacatiș D, Florea A, Bogdan D, Suciu M, Săndulescu R, Cristea C (2017) Highly selective electrochemical detection of serotonin on polypyrrole and gold nanoparticles-based 3D architecture. Electrochem Commun 75:43–47CrossRefGoogle Scholar
  28. 28.
    Gomez FJV, Martín A, Silva MF, Escarpa A (2015) Screen-printed electrodes modified with carbon nanotubes or graphene for simultaneous determination of melatonin and serotonin. Microchim Acta 182:1925–1931CrossRefGoogle Scholar
  29. 29.
    Wang ZH, Xu LJ, Wu GF, Zhu LQ, Lu XQ (2015) Development and application of the serotonin voltametric sensors based on molecularly imprinting technology. J Electrochem Soc 162:B201–B206CrossRefGoogle Scholar
  30. 30.
    Ran G, Chen CN, Gu C (2015) Serotonin sensor based on a glassy carbon electrode modified with multiwalled carbon nanotubes, chitosan and poly (p-aminobenzenesulfonate). Microchim Acta 182:1323–1328CrossRefGoogle Scholar
  31. 31.
    Ran G, Chen X, Xia Y (2017) Electrochemical detection of serotonin based on a poly(bromocresol green) film and Fe3O4 nanoparticles in a chitosan matrix. RSC Adv 7:1847–1851CrossRefGoogle Scholar
  32. 32.
    Sun DF, Li HJ, Li MJ, Li CP, Dai HL, Sun DZ, Yang BH (2018) Electrodeposition synthesis of a NiO/CNT/PEDOT composite for simultaneous detection of dopamine, serotonin, and tryptophan. Sensors Actuators B Chem 259:433–442CrossRefGoogle Scholar
  33. 33.
    Wang F, Wu YJ, Lu K, Ye BX (2013) A simple but highly sensitive and selective calixarene-based voltammetric sensor for serotonin. Electrochim Acta 87:756–762CrossRefGoogle Scholar
  34. 34.
    Babaei A, Taheri AR, Aminikhah M (2013) Nanomolar simultaneous determination of levodopa and serotonin at a novel carbon ionic liquid electrode modified with Co(OH)2 nanoparticles and multi-walled carbon nanotubes. Electrochim Acta 90:317–325CrossRefGoogle Scholar

Copyright information

© Springer-Verlag GmbH Austria, part of Springer Nature 2018

Authors and Affiliations

  1. 1.College of Biological, Chemical Sciences and EngineeringJiaxing UniversityJiaxingPeople’s Republic of China
  2. 2.School of Petrochemical EngineeringChangzhou UniversityChangzhouPeople’s Republic of China
  3. 3.College of Chemistry and Life ScienceZhejiang Normal UniversityJinhuaPeople’s Republic of China

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