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Long-term outcomes of video-assisted thoracoscopic surgery lobectomy vs. thoracotomy lobectomy for stage IA non-small cell lung cancer

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Abstract

Objectives

Video-assisted thoracoscopic surgery (VATS) lobectomy is performed widely for patients with clinical stage I non-small cell lung cancer (NSCLC) because of its superior short-term outcomes to those of thoracotomy lobectomy. However, the long-term outcomes of VATS lobectomy vs. thoracotomy lobectomy remain controversial.

Methods

We reviewed the clinical data of 202 consecutive patients who underwent lobectomy for clinical stage IA NSCLC at our institution between January, 2008 and December, 2013. Stage IA NSCLC was confirmed pathologically in 162 of these patients, 60 of whom underwent VATS lobectomy and 102 of whom underwent thoracotomy lobectomy. We compared the perioperative clinical factors and outcomes of these two groups, using a propensity score-matched analysis.

Results

In an analysis of 58 matched cases, the VATS group showed less blood loss, a shorter duration of chest tube placement, a shorter postoperative hospital stay, and a lower peak C-reactive protein value, despite a longer operative time. The VATS group also had significantly longer survival than the thoracotomy group [5-year overall survival, 100% vs. 87%, respectively (p = 0.01); 5-year disease-free survival, 100% vs. 86% (p = 0.03)].

Conclusions

These findings suggest that VATS may have better long-term as well as short-term outcomes than thoracotomy for patients with early-stage NSCLC.

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Authors and Affiliations

  1. Department of Oncology, Immunology and Surgery, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Nagoya, 467-8601, Japan

    Risa Oda, Katsuhiro Okuda, Takuya Watanabe, Tadashi Sakane, Tsutomu Tatematsu, Keisuke Yokota, Hiroshi Haneda & Ryoichi Nakanishi

  2. Department of Clinical Research Management Center, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan

    Satoshi Osaga

Authors
  1. Risa Oda
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  2. Katsuhiro Okuda
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Correspondence to Katsuhiro Okuda.

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Oda, R., Okuda, K., Osaga, S. et al. Long-term outcomes of video-assisted thoracoscopic surgery lobectomy vs. thoracotomy lobectomy for stage IA non-small cell lung cancer. Surg Today 49, 369–377 (2019). https://doi.org/10.1007/s00595-018-1746-4

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  • DOI: https://doi.org/10.1007/s00595-018-1746-4

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