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Table 4 Major abnormalities detected by the eye-tracking-based test in patients with type 1 diabetes with/without neuropathy

From: Abnormalities of the oculomotor function in type 1 diabetes and diabetic neuropathy

  Healthy subjects T1D without neuropathy T1D with neuropathy P value
Wideness
FrsFixDur 9 (ms) 0.05 ± 0.01 0.04 ± 0.01 0.15 ± 0.03 *0.9; °0.007; §0.03
FrsFixDur 3 (ms) 0.01 ± 0.006 0.05 ± 0.01 0.06 ± 0.01 *0.01; °0.01; §0.4
VisDur3 (ms) 0.02 ± 0.007 0.05 ± 0.01 0.08 ± 0.01 *0.02; °0.01; §0.2
Viscount 9 (n) 0.8 ± 0.1 1.5 ± 0.4 1.9 ± 0.4 *0.09; °0.01; §0.1
Viscount 3 (n) 0.6 ± 1.8 2.1 ± 0.7 4.0 ± 1.3 *0.03; °0.002; §0.07
Viscount 4 (n) 1.1 ± 0.1 1.7 ± 0.2 4.7 ± 1.9 *0.08; °0.03; §0.2
Viscount 5 (n) 0.8 ± 0.1 1.4 ± 0.3 2.0 ± 0.4 *0.1; °0.02; §0.2
Viscount 7 (n) 1.1 ± 0.2 1.6 ± 0.3 4.0 ± 0.7 *0.09; °0.0006; §0.01
Viscount 10 (n) 1.5 ± 0.2 1.4 ± 0.3 14.8 ± 5.0 *0.9; °0.002; §0.004
Resistance
FixCount oq60 (n) 0.6 ± 0.1 1.2 ± 0.1 1.2 ± 0.1 *0.02; °0.04; §0.6
FixDur oq40 DR (ms) 0.2 ± 0.02 0.4 ± 0.07 0.4 ± 0.08 *0.01; °0.01; §0.2
FrsFixDur Numeri Up R (ms) 0.2 ± 0.02 0.5 ± 0.1 0.4 ± 0.06 *0.03; °0.2; §0.4
TimeFrsFix oq80 (ms) 7.0 ± 1.2 15.7 ± 3.3 16.9 ± 5.1 *0.01; °0.01; §0.7
Fixdur Numeri Up R (ms) 0.2 ± 0.02 0.4 ± 0.06 0.3 ± 0.05 *0.005; °0.1; §0.1
Fixcount L80 03 (n) 0.7 ± 0.1 1.4 ± 0.1 1.0 ± 0 *0.005; °0.2; §0.2
Pursuit
VisDur TopDown 1 (ms) 0.2 ± 0.02 0.2 ± 0.02 0.4 ± 0.007 *0.2; °0.0001; §0.0001
TimeFrsFix DxSx 1 (ms) 7.4 ± 0.5 6.8 ± 0.5 4.6 ± 0.3 *0.3; °0.009; §0.03
FrsFixDur TopDown 1 (msec) 0.1 ± 0.02 0.1 ± 0.02 0.2 ± 0.03 *0.2; °0.004; §0.01
Velocity
FrsFixDur L near cross (ms) 0.2 ± 0.03 0.2 ± 0.03 0.4 ± 0.1 *0.1; °0.01; §0.006
Fixcount L far (n) 0.9 ± 0.1 1.2 ± 0.2 2.1 ± 0.4 *0.2; °0.008; §0.03
  1. Data are expressed as mean ± SEM
  2. T1D, Type 1 diabetes; L, left, R, right; DX, right; Sx, left; Fix, fixation; Frs, first; Dur, duration
  3. *Healthy subjects versus T1D without neuropathy; Healthy subjects versus T1D with neuropathy; §T1D without neuropathy versus T1D with neuropathy