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Can HbA1c combined with fasting plasma glucose help to assess priority for GCK-MODY vs HNF1A-MODY genetic testing?

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References

  1. Delvecchio M, Mozzillo E, Salzano G et al (2017) Diabetes Study Group of the Italian Society of Pediatric Endocrinology and Diabetes (ISPED). Monogenic diabetes accounts for 6.3% of cases referred to 15 Italian pediatric diabetes centers during 2007 to 2012. J Clin Endocrinol Metab 102:1826–1834

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Author information

Authors and Affiliations

  1. Pediatric and Neonatology Unit, Mother and Children Health Care Department, “Madonna delle Grazie” Hospital, ASL Matera, Contrada Cattedra Ambulante, 85100, Matera, Italy

    Maurizio Delvecchio

  2. Department of Pediatric Sciences, University of Messina, Messina, Italy

    Giuseppina Salzano & Fortunato Lombardo

  3. Endocrine Unit, Department of Pediatrics, Diabetes Research Institute (OSR-DRI), Scientific Institute Hospital San Raffaele, Milan, Italy

    Clara Bonura

  4. Pediatric Diabetology Unit, S. Chiara Hospital, Trento, Italy

    Vittoria Cauvin

  5. S.O.D. Pediatric Diabetology, Department of Women’s and Children Health, Salesi Hospital, Ancona, Italy

    Valentino Cherubini

  6. Istituto Giannina Gaslini, Regional Center for Pediatric Diabetes, Genoa, Italy

    Giuseppe d’Annunzio

  7. Regional Center of Pediatric Diabetology, University of Naples Federico II, Naples, Italy

    Adriana Franzese

  8. Medical Genetics Unit, Department of Clinical and Experimental Biomedical Sciences “Mario Serio”, and Meyer Children’s University Hospital, University of Florence, Florence, Italy

    Sabrina Giglio

  9. Department of Experimental Medicine and Surgery, University of Rome Tor Vergata, Via Montpellier 1, 00133, Rome, Italy

    Valeria Grasso & Fabrizio Barbetti

  10. Pediatric Unit, S. Maria delle Croci Hospital, AUSL della Romagna, Ravenna, Italy

    Vanna Graziani

  11. Department of Pediatrics, Regional Center for Pediatric Diabetology “G.Stoppoloni”, University of Campania “Luigi Vanvitelli”, Naples, Italy

    Dario Iafusco

  12. Pediatric Unit, Department of Medical and Surgical Sciences for Mothers, Children and Adults, University of Modena and Reggio Emilia, Modena, Italy

    Lorenzo Iughetti

  13. Department of Pediatrics, Alessandria Hospital, Alessandria, Italy

    Riccardo Lera

  14. Pediatric Diabetes and Metabolic Disorders Unit, Department of Surgical Science, Dentistry, Ginecology and Pediatrics, University of Verona, Verona, Italy

    Claudio Maffeis

  15. Department of Pediatrics, S. Orsola-Malpighi University Hospital, Bologna, Italy

    Giulio Maltoni

  16. Center for Applied Biomedical Research (CRBA) and Medical Genetics Unit, St. Orsola University Hospital, Bologna, Italy

    Vilma Mantovani

  17. Research Unit of Diabetes and Endocrine Disease, IRCCS Casa del Sollievo della Sofferenza, San Giovanni Rotondo (FG), Italy

    Claudia Menzaghi

  18. Pediatric Diabetology Unit, University Department of Pediatric Medicine, Bambino Gesù Children Hospital, Rome, Italy

    Patrizia I. Patera

  19. Department of Pediatrics, Regina Margherita Children Hospital, Turin, Italy

    Ivana Rabbone

  20. Department of Pediatrics, General Hospital Bolzano, Bolzano, Italy

    Petra Reindstadler

  21. Pediatric Diabetes Unit, Health Service of Caltanissetta, Caltanissetta, Italy

    Sabrina Scelfo

  22. Department of Molecular Medicine and Medical Biotechnology, University of Naples Federico II, and CEINGE, Advanced Biotechnology, Naples, Italy

    Nadia Tinto

  23. Juvenile Diabetes Center, Meyer Children’s Hospital, Florence, Italy

    Sonia Toni

  24. Center of Pediatric Diabetology, University of Chieti, Chieti, Italy

    Stefano Tumini

  25. CORESEARCH-Center for Outcomes Research and Clinical Epidemiology, Pescara, Italy

    Antonio Nicolucci

  26. Bambino Gesù Children’s Hospital, IRCCS, Rome, Italy

    Fabrizio Barbetti

Authors
  1. Maurizio Delvecchio
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  2. Giuseppina Salzano
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  3. Clara Bonura
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  4. Vittoria Cauvin
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  5. Valentino Cherubini
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  6. Giuseppe d’Annunzio
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  7. Adriana Franzese
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  8. Sabrina Giglio
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  9. Valeria Grasso
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  10. Vanna Graziani
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  11. Dario Iafusco
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  12. Lorenzo Iughetti
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  13. Riccardo Lera
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  14. Claudio Maffeis
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  15. Giulio Maltoni
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  16. Vilma Mantovani
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  17. Claudia Menzaghi
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  18. Patrizia I. Patera
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  19. Ivana Rabbone
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  20. Petra Reindstadler
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  21. Sabrina Scelfo
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  22. Nadia Tinto
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  23. Sonia Toni
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  24. Stefano Tumini
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  25. Fortunato Lombardo
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  26. Antonio Nicolucci
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  27. Fabrizio Barbetti
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Consortia

The Diabetes Study Group of the Italian Society of Pediatric Endocrinology and Diabetes (ISPED)

Contributions

All Authors and contributors researched data and critically reviewed the paper. MD collected data, performed statistics and drafted the paper. AN performed statistics. FB, the guarantor of the paper, conceived the study, collected data, and critically revised the manuscript.

Corresponding authors

Correspondence to Maurizio Delvecchio or Fabrizio Barbetti.

Ethics declarations

Conflict of interest

Authors have no conflict of interest to declare.

Human and animal rights

All procedures performed in this study were in accordance with the ethical standards of the institutional and/or national research committe and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

Fot this type of study formal consent is not required.

Additional information

Managed by Massimo Porta.

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Delvecchio, M., Salzano, G., Bonura, C. et al. Can HbA1c combined with fasting plasma glucose help to assess priority for GCK-MODY vs HNF1A-MODY genetic testing?. Acta Diabetol 55, 981–983 (2018). https://doi.org/10.1007/s00592-018-1179-y

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  • DOI: https://doi.org/10.1007/s00592-018-1179-y

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