European Spine Journal

, Volume 27, Issue 4, pp 841–846 | Cite as

Assessment of paraspinal neurogenic tumors with diffusion-weighted MR imaging

  • Ahmed Abdel Khalek Abdel Razek
  • Germeen Albair Ashmalla
Original Article



To assess paraspinal neurogenic tumors with diffusion-weighted MR imaging.


Retrospective analysis was done upon 34 patients with paraspinal neurogenic tumors that underwent diffusion-weighted MR imaging. The ADC values of the mediastinal neurogenic tumors were calculated and correlated with biopsy results.


The ADC of benign paraspinal neurogenic tumors (1.5 ± 0.28 × 10−3 mm2/s) was significantly higher (P = 0.001) than that of malignant peripheral nerve sheath tumors (0.995 ± 0.198 × 10−3 mm2/s). Selection of 1.15 × 10−3 mm2/s as a cut-off point for differentiating malignant from benign neurogenic tumors revealed an area under the curve of 0.885, an accuracy of 91.1%, a sensitivity of 90.9%, and specificity of 91.3%. There was significant difference (P = 0.04) in the ADC of schwannomas (1.55 ± 0.29 × 10−3 mm2/s) from neurofibromas (1.33 ± 0.08 × 10−3 mm2/s). The cut-off ADC value of 1.44 × 10−3 mm2/s was used to differentiate schwannomas and neurofibromas with an area under the curve of 0.86, an accuracy of 82.6%, a sensitivity of 100%, and a specificity of 76.5%.


Diffusion-weighted MR imaging is imaging parameter that can be used for differentiation of benign from malignant paraspinal neurogenic tumors.


Diffusion Paraspinal Neurogenic MR imaging 


Compliance with ethical standards

Conflict of interest

Authors declare that they have no competing interest.


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Copyright information

© Springer-Verlag GmbH Germany 2017

Authors and Affiliations

  1. 1.Department of Diagnostic RadiologyMansoura Faculty of MedicineMansouraEgypt

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